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Sister Chromatid
identical halves of a duplicated parent chromosome that are held together by a centromere. identical tightly coiled halves of a duplicated chromosome
Chromatin
loose, uncondensed, long strands of DNA found in the eukaryotic cell nucleus; condense to form chromosomes. fills the nucleus during most of the cell cycle.
Centromere
region of chromosome that holds two sister chromatids together during mitosis
Cell division
the process by which a cell divides into two new daughter cells
Mitosis
cell division in which the nucleus divides into nuclei containing the same number of chromosomes
Cell Cycle
series of events that cells go through as they grow and divide. Interphase + Mitosis
G1
Growth phase 1; cell grows and makes proteins.
cellular contents excluding the chromosomes, are duplicated
S phase
DNA Synthesis
Cell continues to grow as it copies its chromosomes
Each of the 46 chromosomes are duplicated by the cell
G2
Gap 2
Cell grows more as it completes preparations of cell division. cell '“Double checks” the duplicated chromosomes for error, making any needed repair
Mitotic Phase
Stage of the cell cycle where the cell is actively dividing.
Cytokinesis
Stage of cell cycle where cytoplasm divides.
Interphase
period of the cell cycle during which the nucleus is NOT undergoing division, typically occurring between mitotic or meiotic divisions
includes g1, g2, and 2 phase
Prophase (Mitosis)
chromatin condenses into chromosomes becomes visible
nuclear envelope breaks down
centrosomes begin to move to opposite sides
centrioles form and move toward opposite ends of the cell, the poles
spindle fibers from each centriole attach to each sister chromatid at the kinetochore
Centrosome
cellular structure involved in the process of cell division. Duplicates and then, as division begins, two centrosomes move to opposite ends of the cell two centrioles. centrosomes organize the microtubules as they pull APART.
Mitotic Spindle
An assemblage of microtubules and associated proteins that is involved in the movements of chromosomes during mitosis.
Spindle microtubules/fibers
The filaments are responsible for moving chromosomes during cell division.
fibers that attach to chromosomes and move the chromosomes by pulling homologous chromosomes opposite directions and pushing the poles apart
Kinetichore
a specialized region on the centromere that links each sister chromatid to the mitotic spindle
Metaphase
second phase of mitosis, during which the chromosomes line up across the center of the metaphase plate
Anaphase
Begins when the two centromeres of each chromosome come apart, separating the sister chromatids. Elongates the cell.
Telophase
the final stage of mitosis or meiosis, during which a nuclear membrane forms around each set of new chromosomes
Cleavage Furrow
the first sign of cytokinesis during cell division in an animal cell; a shallow groove in the cell surface near the old metaphase plate
Cell Plate
A double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis.
Cell Cycle Control System
A cyclically operating set of molecules in the cell that triggers and coordinates key events in the cell cycle.
Tumor
an abnormal new mass of tissue that serves no purpose (caused by overproduction and buildup of cells)
Somatic Cell
any of the cells of a plant or animal except the reproductive cells
Sex chromosomes
one of the 23 pairs of chromosomes in the human, contains genes that will determine the sex of the individual
Autosomes
chromosomes that are not directly involved in determining the sex of an individual
Diploid
(genetics) an organism or cell having two sets of chromosomes or twice the haploid number
Haploid
(genetics) an organism or cell having only one complete set of chromosomes
Gametes
sex cells
Fertilization
creation by the physical union of male and female gametes
Zygote
fertilized egg or the product of two joined gametes
Meiosis
(genetics) cell division that produces reproductive cells in sexually reproducing organisms
Prophase 1 (Meiosis)
DNA coils tightly into chromosomes and spindle fibers appear; the nucleolus and nuclear membrane disassemble and every chromosomes lines up next to its homologue. During this process, the chromosomes within a homologous pair twist around one another. Crossing-over, or the exchange of genetic material between maternal and paternal chromosomes may occur.
Metaphase 1 (Meiosis)
pairs of homologous chromosomes, line up randomly along the midline of the dividing cell. Spindle fibers from one pole attach to the centromere of one homologous chromosome and spindle fibers from the opposite pole attach to the other chromosome of the pair.
Homologous Chromosome
one of a matching pair of chromosomes, one inherited from each parent
Homologs
Matching Chromosomes that are similar but not identical
Anaphase 1 (Meiosis)
homologous chromosomes seperate
Telophase 1 (Meiosis)
Chromosomes reach the opposite ends of the cell and cytokinesis begins.
Cytokinesis (Meiosis)
The cell splits into 2 daughter cells with 2 chromatids in each. The chromosomes are different from each other and from the parent diploid cell because of the crossing over that occurred in Prophase I.
Meiosis II
The second division of a two-stage process of cell division in sexually reproducing organisms that results in cells with half the chromosome number of the original cell.
Tetrad
structure containing 4 chromatids that forms during meiosis
Crossing over
the interchange of sections between pairing homologous chromosomes during the prophase of meiosis (reorganization)
karyotype
A picture of all the chromosomes in a cell arranged in pairs
nondisjunction
meiosis in which there is a failure of paired homologous chromosomes to separate
Centriole
role in organizing microtubules that serve as the cell’s skeletal system.
Help determine the locations of the nucleus.
Made up of microtubules
Centrioles go to opposite ends of the nucleus
mainly in animals
kinetochores
a specialized structure on the centromere to which the microtubular spindle fibers attach during mitosis and meiosis
prometaphase
transitional stage in mitosis ( cell division) between prophase and metaphase.
Nuclear envelope breaks down, allowing spindle fibers to enter the nucleus and attach to the chromosomes at their kinetochores, initiating chromosome movement towards the cell’s center.
follows prophase.