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Psychiatry
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What is Anorexia Nervosa?
Loss of body weight and refusal to eat, despite appetite being intact. Intense fear of gaining weight. BMI < 18.5 is common.
What is Bulimia Nervosa?
Recurrent binge eating episodes with or without vomiting or other compensatory behaviors. Patients typically maintain a normal body weight.
What is Binge Eating Disorder?
A variant of bulimia nervosa characterized by binge eating without purging. Occurs >1x/week
What is Pica?
The eating of non-nutritional substances, such as dirt, paper, or chalk.
What is Rumination Disorder?
Repeated regurgitation of food, often seen in infancy or childhood.
What is Avoidant/Restrictive Food Intake Disorder?
Lack of interest in food or avoidance of eating, leading to failure to thrive.
What are the 3 core features of Anorexia Nervosa?
Self-induced starvation
Drive for thinness / fear of fatness
Physiologic symptoms from starvation (e.g., lanugo, heart failure, electrolyte imbalance)
How long must symptoms of Anorexia Nervosa persist for diagnosis?
At least 3 months
What are the 2 subtypes of Anorexia Nervosa?
Restricting type: limits intake to 300–500 calories/day
Binge-purging type: uses laxatives, vomiting, or excessive exercise
What is the typical onset and prognosis for Anorexia Nervosa?
Onset: Ages 10–20s
Comorbidity: 50% have Major Depressive Disorder
Mortality: 5–18% (poor prognosis)
What is the First line treatment for Anorexia Nervosa?
FIRST LINE- Psychotherapy (mainstay)
Hospitalization if medically unstable (avoid refeeding syndrome)
Pharmacotherapy: SSRIs for comorbid depression (fluoxetine, sertraline, fluvoxamine)
Avoid TCAs in emaciated patients
Bupropion is contraindicated- lowers seizure threshold
In short:
You avoid refeeding syndrome because restarting nutrition too quickly after starvation can cause life-threatening electrolyte shifts and heart failure.
Which medication can be used to treat anorexia and treats depression plus helps with weight gain?
Olanzapine.Â
What are the key features of Bulimia Nervosa?
Recurrent binge eating with compensatory behaviors (vomiting, laxatives, etc.)
Occurs ≥1/week for 3 months
Normal weight; intense fear of fatness
Onset: Late teens to early 20s
In which eating disorder is Russell sign seen, and what is it?
Bulimia nervosa
Calluses/abrasions on the dorsum of the hand from repeated contact with teeth during self-induced vomiting.
What is the First Line treatment for Bulimia Nervosa?
FIRST LINE- Psychotherapy: Cognitive Behavioral Therapy (CBT)
Outpatient: Nutritional rehabilitation
Pharmacotherapy: SSRIs (fluoxetine, sertraline, fluvoxamine)
Avoid bupropion – lowers seizure threshold
What are the key features of Binge Eating Disorder?
Binges with 4 features:
Eating rapidly
Eating until uncomfortably full
Eating when not hungry
Eating alone → guilt or distress
Frequency: ≥1/week for 3 months
Weight: Usually overweight or obese
What is the first line treatment for Binge Eating Disorder?
CBT (most effective)
Medications: trazodone or bupropion (can help with cravings)
Exercise + Self-help groups
What is the key pharmacologic distinction among eating disorders?
Anorexia & Bulimia: ❌ Bupropion contraindicated (seizure risk)
Binge Eating Disorder: âś… Bupropion can be used safely
What are the 2 core symptom categories of ADHD?
Inattention
Hyperactivity/impulsivity
When do symptoms of ADHD typically appear?
Often observed by age 4, peak by age 7, and may lessen with age
What is the first-line treatment for ADHD in school-aged children?
Behavioral therapy (especially in school settings)
Add medication if therapy fails or by age 6
What are stimulant medications for ADHD?
Methylphenidate (Ritalin)
Dexmethylphenidate (Focalin)
Amphetamine XR (Adderall XR)
Lisdexamfetamine (Vyvanse)
Contraindications: anxiety, hyperthyroidism, motor tics, glaucoma, substance abuse, MAOIs
What is the main non-stimulant for ADHD?
Atomoxetine (Strattera)
Side effects: tics, suicidal ideation, priapism, weight loss
What is the underlying pathophysiology of ADHD?
Impaired dopamine and norepinephrine signaling in frontostriatal circuits
What defines Autism Spectrum Disorder?
Chronic neurodevelopmental condition with deficits in social, communication, and behavioral function
What are early signs of ASD?
Poor social/language skills
Avoiding eye contact, prefers being alone
Trouble understanding others’ emotions
Repetitive behaviors or obsessive interests
Unusual sensory reactions
When are ASD symptoms usually recognized?
Parents notice signs by age 2
Formal diagnosis around age 4
What are treatments for ASD?
Behavioral and educational interventions
Pharmacologic support for specific symptoms
Alternative therapies as adjuncts
What are the differential diagnoses for ASD? *not important
Intellectual disability
Social communication disorder
Fetal alcohol spectrum disorder
ADHD
Anxiety disorders
What defines a Paraphilic Disorder?
Arousal to atypical objects, situations, or individuals, causing distress or harm