BISC 220 - Pyruvate Oxidation

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4 Terms

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Where does Pyruvate oxidation occur?

in the mitochondrial MATRIX

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What are the products of Pyruvate oxidation per one molecule of glucose?

2 carbon dioxides, 2 molecules of Acetyl CoA, and more NADH,

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Explain what happens during Pyruvate oxidation

  1. After glycolysis, a transport protein moves the 2 pyruvate into the mitochondrial matrix

  2. Nonpolar covalent C —- C bond is broken, NADH is produced and the energy released is used to form CO2 molecules

  3. Coenzyme A (CoA) attaches to the remaining molecule to make Acetyl CoA

  4. Acetyl CoA is fed into the citric acid (krebs) cycle

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What happens with electron carriers during pyruvate oxidation?

NAD+ picks up electrons released from pyruvate, which reduces it to NADH. NADH will transfer these electrons for energy production in later pathways