T-cell receptor signaling molecules 2

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Last updated 12:16 AM on 2/21/25
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4 Terms

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Why is peptide loading onto MHC molecules important?

Peptide loading onto MHC molecules is vital for the successful activation of T cells.

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Where are MHC class I molecules loaded with peptides?

MHC class I molecules are loaded with peptides from intracellular proteins in the endoplasmic reticulum (ER).

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What happens after MHC class I molecules are loaded with peptides?

After loading, MHC class I molecules move to the plasma membrane and present peptides to CD8 T cells.

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