T-cell receptor signaling molecules 2
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Why is peptide loading onto MHC molecules important?
Peptide loading onto MHC molecules is vital for the successful activation of T cells.
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Where are MHC class I molecules loaded with peptides?
MHC class I molecules are loaded with peptides from intracellular proteins in the endoplasmic reticulum (ER).
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What happens after MHC class I molecules are loaded with peptides?
After loading, MHC class I molecules move to the plasma membrane and present peptides to CD8 T cells.
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