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inflammation
The body's general response to tissue injury, intended to neutralize harmful agents, clear damaged tissue, and prepare for healing
acute inflammation
Inflammation with a rapid onset that typically lasts 8 to 10 days from injury to healing
chronic inflammation
Inflammation that persists for weeks to years and involves different cells like macrophages and lymphocytes , often leading to tissue damage and fibrosis. It can result from a failure to eliminate the cause of acute inflammation or autoimmune responses.
vascular phase
The initial stage of inflammation involving brief vasoconstriction followed by vasodilation and increased capillary permeability, leading to plasma flow into tissues
cellular phase
The stage where neutrophils infiltrate the injured area to attack organisms through phagocytosis
histamine
A chemical mediator that increases capillary permeability, allowing fluid and immune cells to move into tissues
prostaglandins
Chemical mediators that cause vasodilation and contribute to the sensation of pain
cytokines
regulate immune and inflammatory responses by facilitating communication between cells.
complement system
A group of proteins that promote phagocytosis and cell lysis
ambulatory surical center
An outpatient setting where surgeries are performed that do not require an overnight hospital stay; often used for less complex procedures
minimally invasive surgery
Surgical techniques using smaller incisions and advanced technology (like endoscopes and robots) to reduce blood loss, tissue trauma, and recovery time; an example is a "Lap Colie"
lap cholie
A minimally invasive procedure to remove the gallbladder using small incisions and a laparoscope (thin tube with a camera
osteroporosis
A condition characterized by weak and brittle bones, increasing the risk of fractures and breaks. It commonly occurs due to hormonal changes, lack of calcium or vitamin D, and aging. be careful with surgical positioning to prevent long term injury or disability
osteoarthritis
A degenerative joint disease characterized by the breakdown of cartilage, leading to pain, stiffness, and reduced mobility, commonly associated with aging or joint injury. be careful with surgical positioning to prevent long term injury or disability
48
patients should avoid shaving for ____ hours before surgery
antidepressents
can increase the effect of opioids used for pain/anesthesia
antihypertensives
may predispose patient to hypotension from combined affect of drug and vasodilating anesthesias
insulin
may need to be adjusted when taking opioids because opioids can alter blood sugar levels.
antiplatelets
medications like aspirin and NSAIDs may contribute to post op bleeding, ask about herbal supplements
Chlorhexidine Gluconate
Patients shower with _______ (CHG/Hibiclens) from the neck down (avoiding face/hair/genitals) the night before and morning of surgery to reduce microorganisms
48
Patients should not shave for at least __hours before surgery to prevent micro-cuts that increase infection risk; if hair removal is needed, it is done at the facility immediately before surgery
positive air pressure system
Specialized ventilation in the OR that prevents air from the corridors from entering the sterile room
time out
A required safety pause immediately before surgery where the entire team verifies the patient ID, procedure, surgical site (marked by the surgeon), and allergies
sentinel event
A serious, preventable error in the OR, such as surgery on the wrong body part, wrong procedure, or wrong patient
circulating nurse
registered nurse who works outside the sterile field, managing documentation, patient positioning, and acting as the patient's advocate
scrub nurse
A member of the team who performs a surgical hand scrub, dons sterile attire, and handles only sterile items within the sterile field
general anesthesia
Causes complete loss of consciousness, memory, and sensation; requires an artificial airway (intubation) and carries risks of hypotension and nausea
regional anesthesia
Numbing a large region (like an arm or the lower half of the body) while the patient remains awake and can breathe on their own; examples include epidurals or spinal blocks
moderate sedation
A combination of sedation and pain control where the patient is relaxed and drowsy but can maintain their own airway; often used for colonoscopies
local anesthesia
Numbing a small, specific area (e.g., for a skin biopsy or dental work) while the patient remains fully awake
malignant hyperthermia
A rare, life-threatening hypermetabolic crisis triggered by general anesthesia agents; characterized by muscle rigidity (especially the jaw), tachycardia, and extreme fever (up to 110°F)
immediately discontinue of triggering anesthetic agents and administer dantrolene, along with aggressive body cooling and supportive care
dantrolene
the definitive antidote medication for Malignant Hyperthermia
spinal headache
A severe headache caused by the leakage of cerebrospinal fluid after a spinal or epidural procedure
lateral recovery position
Placing a patient on their side until they are conscious to keep the airway open and reduce the risk of aspiration
atelectasis
The collapse of alveoli due to shallow breathing or mucus plugs; it is the most common cause of hypoxemia in the post-op period
pulmonary edema
Fluid accumulation in the alveoli, often caused by fluid overload or aspiration; characterized by shortness of breath and crackles
pulmonary embolism
A blockage in a pulmonary artery, often by a blood clot from the leg (DVT); symptoms include sudden chest pain, shortness of breath, and tachycardia.
brochospasm
Closure of small airways due to increased smooth muscle tone; characterized by wheezing and use of accessory muscles
splinting
Using a pillow or folded blanket to support an abdominal or chest incision while coughing or taking deep breaths
DVT
A blood clot in a leg vein due to inactivity; prevented by early ambulation, SCDs, and anticoagulants
emergence delirium
A temporary state of confusion or agitation as the patient wakes up; "awake but not clear," often caused by hypoxemia
delayed emergence
When a patient remains unusually drowsy or sedated and does not wake up as expected after anesthesia
postoperative ileus
A decrease in gastric peristalsis; characterized by absent or decreased bowel sounds and abdominal distension
30
A patient should output at least ____mL per hour; lower output (oliguria) may indicate renal failure or poor perfusion
dehiscence
The partial or complete separation of closed wound edges (the incision "opens up")
evisceration
A surgical emergency where the wound opens wide enough for internal organs (like intestines) to protrude.
Stay with the patient, place them in low Fowler's, cover the wound with a sterile, moist saline dressing, and notify the surgeon immediatel
hyperemia
Increased blood flow to an area caused by arterials dilating; it is responsible for the redness and heat seen in inflammation
acute inflammation
Inflammation characterized by the predominance of neutrophils
chronic inflammation
inflammation characterized by the presence of macrophages and lymphocytes
histamine
A chemical mediator that increases capillary permeability, allowing fluid and immune cells to move into tissues
prostaglandins
Chemical mediators that cause vasodilation and sensitize nerve cells to create the sensation of pain
complement system
A group of proteins that promote phagocytosis and cell lysis to destroy pathogens
shift to the left
An increase in the production of immature white blood cells (called bands), indicating an acute bacterial infection or inflammation
malaise
A systemic manifestation of inflammation described as a general feeling of fatigue or being unwell
innate immunity
Protection present at birth that responds immediately to threats using physical barriers (skin/mucous membranes) and phagocytes; no prior exposure is needed
acquired/adaptive immunity
Immunity that develops after exposure to an antigen, providing long-lasting protection and immunological memory through B and T cells
natural active immunity
Immunity developed through natural contact with an antigen via an actual infection (e.g., chickenpox)
natural passive immunity
Immediate but short-lived immunity transferred from mother to child via the placenta or breast milk
artificial active immunity
Long-lasting immunity developed through immunization with vaccines
artificial passive immunity
Immediate but short-lived immunity provided by an injection of serum containing antibodies (e.g., Hepatitis B immune globulin
humoral immunity
Antibody-mediated immunity involving B cells that fight extracellular threats (bacteria/toxins) in body fluids
cell mediated immunity
Immunity involving T cells that act directly against intracellular threats like viruses and cancer cells
spleen
The primary organ site for filtering foreign antigens from the blood
thymus
The site for differentiation and maturation of T lymphocytes; it is located in the chest and shrinks with age
nociceptive pain
Pain resulting from actual tissue injury or inflammation
neuropathic
Pain resulting from nerve injury or dysfunction, often described as a "tingling" sensation
mcburneys point
The classic location for appendicitis pain, located between the anterior iliac crest and the umbilicus (Right Lower Quadrant)
10,000-18,000
A WBC count between _____ indicates infection of appendix
20,000
A WBC count above _____ indicates preforation of appendix
osteoarthritis
A progressive, degenerative joint disease involving the breakdown of articular cartilage, leading to bone rubbing on bone
Typically an asymmetrical joint pattern; pain worsens with activity and improves with rest
herberden nodes
bony growths on the joint tips of fingers associated with osteoarthritis.
bouchard nodes
bony growths on the middle joints of fingers associated with osteoarthritis.
osteophytes
bone spurs often seen in osteoarthritis
gout
A disorder of uric acid metabolism leading to hyperuricemia (excess uric acid in the blood) and crystal formation in joints
HIV
A retrovirus that targets CD4+ T-helper cells, replicating backward from RNA to DNA using reverse transcriptase
800-1200
Normal CD4 Count
AIDS
A CD4 T-cell count of less than 200 cells/mm³ or the presence of an opportunistic infection
ventilation
The movement of air into and out of the lungs
perfusion
The movement of blood through the capillary beds of the lungs to the body's organs and tissues
diffusion
The movement of gases (oxygen and carbon dioxide) down their concentration gradients across the alveolar-capillary membrane
alveoli
The tiny air sacs in the lungs where gas exchange occurs; they must be thin, pliant, and clear of mucus to function properly
atelectasis
The collapse of alveoli, which prevents normal gas exchange; often caused by shallow breathing or mucus plugs after surgery
sinusitis
Inflammation of the sinuses, usually following a viral infection, where trapped mucus causes facial pressure and pain
rheumatic fever
A serious complication of untreated strep throat that can damage heart valves; prevented by a full 10-day course of penicillin
community acquired pneumonia
An infection contracted in daily life by a patient who has not been hospitalized within 14 days of getting sick
hospital acquired pneumonia
An infection that starts 48 hours or longer after hospital admission
aspiration pneumonia
Caused by inhaling food, saliva, or gastric contents; prevented by turning unconscious patients on their side and monitoring those with swallowing problems
latent tb
The bacteria are "walled off" in a jail cell (Ghon focus); the patient has a positive skin test but no symptoms and is not contagious
active tb
The bacteria are in "attack mode"; the patient is symptomatic and infectious, often presenting with a dry/productive cough and night sweats
asthma
A reversible obstructive disease characterized by bronchial hyper-reactivity (twitchy lungs) and bronchoconstriction
inhaled corticosteroid
Long-term "controller" meds used daily to reduce inflammation; patients must rinse their mouth after use to prevent thrush
pulmonary function tests
Measures lung volumes; patients should hold bronchodilators for 6–12 hours and not smoke for 6–8 hours prior to the test
HIV
complex bloodborne retrovirus that causes significant immunosuppression by targeting and destroying CD4+ T-helper cells. These cells are essential regulators of the immune system, and their destruction leaves the body vulnerable to opportunistic infections and certain cancers
cd4 T cells
HIV is a complex bloodborne retrovirus that causes significant immunosuppression by targeting and destroying _______
200
Acquired Immunodeficiency Syndrome is defined by a CD4 T-cell count of less than _____ cells/mm³ or the presence of opportunistic infections, such as Pneumocystis pneumonia (PJP), oral thrush, or pulmonary tuberculosis
800-1200
normal CD4 cell count is
Antiretroviral Therapy
A treatment for HIV that uses a combination of medications to manage the virus, reduce viral load, and maintain immune function.
green zone
PEFR of 80-100%, indicates patient's asthma is under good control
yellow zone
PEFR of 50-80%, It serves as a warning shot that the asthma is worsening and a flare-up is starting.
The patient must follow their pre-written Asthma Action Plan to ramp up their rescue medication