Oxidative Phosphorylation

What happens to the H+ in the inter membrane space

it needs to enter the matrix of the mitochondria

how does the H+ enter the matrix

oxidative phosphorylation

what is oxidative phosphorylation

process of H+ ions moving into the matrix via ATP synthase

what direction does H+ move during oxidative phosphorylation

hi → low

passive transport

what is atp synthase

an enzyme complex

what does atp synthase do 

-H+ ion channel (inter membrane space → matrix)

-enzyme

what happens when H+ moves through ATP synthase

when it moves through the channel it activates enzyme which catalyzes chemical reaction creating ATP

what does the movement of H+ ions from i.m to the matrix provide energy for

ATP synthase 

what chemical reaction is catalyzed in ATP synthase

phosphorylation of ADP

ADP + P_i → ATP

how much ATP is made during phosphorylation of ADP

32-34 depending upon PMF size (proton motor force)

PMF size determines what

how many times ATP synthase activates 

how much ATP is made from Aerobic C.R

Total: 34-38

2- glycolysis

2-kreb cycle

32-34- oxidative phosphorylation

oxidative phosphorylation is coupled with what?

this means…

oxidative phosphorylation is coupled with the electron transport chain, this means they are interdependent on each other 

what do mitocndrial inhibitors 

poison that can affect atp production since its made in the mitochondria

cyanide

competitive complex IV inhibitor

FCCP

photonophore

makes holes in the inner membrane

oligomycin

atp synthase inhibitor

-blocks H+ channel