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What is skeletal cartilage?
highly resilient, molded cartilage tissue that consists primarily of water.
True or False:
Skeletal Cartilage contains no blood vessels or nerves.
True
What is the Perichondrium?
Layer of dense connective tissues surrounding cartilage like a girdle.
What does Perichondrium help in?
helps cartilage resist outward expansion.
What is cartilage made up of?
Chondrocytes
What are chondrocytes?
Cells encased in small cavities (lacunae) within jelly-like extracellular matrix.
What are the 3 types of cartilage?
Hyaline, Elastic, Fibrocartilage
What is hyaline cartilage?
Provides support, flexibility, and resilience
True or False:
Hyaline cartilage does NOT contain collagen fibers only.
False
Where is hyaline cartilage seen?
Articular (joints), costal (ribs), respiratory (larynx), nasla cartilage (nose tip)
What is elastic cartilage?
similar to hyaline cartilage, but contains elastic fibers
Where can you find elastic cartilage?
in the external ear and epiglottis
What is fibrocartilage?
Thick collagen fibers which have great tensile strength.
Where can you find fibrocartilage?
Menisci of knee, vertebral discs
What are the 7 important functions of bones?
Support
Protection
Movement
Mineral and growth factor storage
Blood cell formation
Triglyceride (fat) storage
Hormone production
What does Support do?
For body and soft organs
What does Protection do?
Protect brain, spinal cord, and vital organs.
What does Movement do?
Levers for muscle action
What does Mineral and growth factor storage do?
Calcium and phosphorus, and growth factors reservoir
Where does hematopoiesis do?
occurs in red marrow cavities of certain bones
What is triglyceride (fat) storage?
Fat, used for an energy source, is stored in bone cavities
What is osteocalcin?
it is secreted by bones and helps to regulate insulin secretion, glucose levels, and metabolism
How many named bones are there in the human skeleton?
206
True or False:
Bones are divided into two groups based on location?
True
What are the two groups of bones?
Axial skeleton
Appendicular skeleton
What does the Axial skeleton consist of?
Long axis of body, skull, vertebral column, ribs
What does the Appendicular skeleton consist of?
bones of the upper/lower limbs, girdles attaching limbs to axial skeleton
Bones are classified into 1 of 4 shapes. What are they?
long bones
short bones
flat bones
irregular bones
Describe long bones:
Longer than they are wide
limb bones
Describe short bones:
cube-shaped bones (in wrist and ankles), they vary in size and number in different individuals
Where do sesamoid bones form?
They form within tendons
(EX: Patella)
Describe flat bones:
thin, flat, slightly curved
(EX: sternum, scapulae, ribs, most skull bones)
Describe Irregular bones:
complicated shapes
(EX: vertebrae and hip bones)
What classification is a limb bone?
Long bones
What classification are wrists and ankle bones?
Short bones
What classification would a patella bone be?
Short bone
What classification would the sternum be?
Flat bone
What bone classification would the scapulae be?
Flat bone
What bone classification would the ribs be?
flat bones
What bone classification would most skull bones be?
Flat bone
What bone classification would the vertebrae be?
irregular bones
What bone classification would the hip bones be?
irregular bones
True or False:
Bones ARE organs because they contain different types of tissues.
True
True or False:
A Bone contains nervous tissue, cartilage, fibrous connective tissue, muscle cells, and epithelial cells in its blood vessels.
True
What are the 3 levels of structure for bones?
gross
microscopic
chemical
What is compact bone?
dense outer layer on bones that appear smooth and solid.
What is spongy bone?
made up of “honeycomb” of small-needle-like or flat pieces of bone called trabeculae.
True or false:
Open spaces between trabeculae ARE filled with red or yellow bone marrow.
True
True or false:
Spongy bone has a mesh of bony spines called trabeculae
True
True or false:
Compact bone does NOT look smooth and solid
False
(compact bone appears smooth and solid)
What does the structure of short, irregular, and flat bones consist of?
thin plates of spongy bone covered by compact bone
What is another word for spongy bone?
diploe
True or False:
Compact bone IS sandwiched between connective tissue membranes.
True
What is the periosteum?
It covers the OUTSIDE portion of compact bone.
What is the Endosteum?
It covers the INSIDE portion of compact bone.
Where is bone marrow scattered throughout?
spongy bone
What does hyaline cartilage cover?
area of bone that is part of a movable joint.
What is the “shaft” and also forms the long axis of a long bone?
diaphysis
What is the end of a long bone called?
epiphyses
True or false:
The Epiphyses consists of compact bone externally and spongy bone internally
True
True or False:
Articular cartilage does NOT cover articular (joint) surfaces.
False
( articular cartilage does cover articular joint surfaces)
What is between the diaphysis and epiphysis?
Epiphyseal line
What occurs in epiphyseal plate?
bone growth
What are the 2 membranes?
periosteum
endosteum
What is the periosteum?
white, double-layered membrane that covers the EXTERNAL surfaces except joints.
What is the fibrous layer?
outer layer consisting of dense irregular connective tissue that consists of Sharpey’s fibers that secure bone to matrix.
What is the Osteogenic layer?
inner layer abutting bone and contains primitive osteogenic stem cells.
True or False:
The periosteum contains many nerve fibers and blood vessels that continue on to the shaft through nutrient foramen openings.
True
True or false:
The periosteum is NOT an anchoring point for tendons and ligaments.
False
What does the endosteum cover?
it is a delicate connective tissue membrane that covers internal bone surace.
True or false:
The endosteum covers trabeculae of spongy bone.
True
True or false:
The endosteum does NOT line canals that pass through compact bone.
FALSE
Does the endosteum contain osteogenic cells?
Yes, just like the periosteum they both can differentiate into other bone cells.
Where is Red marrow found?
within trabecular cavities of spongy bone and diploe of flat bones. such as sternum
True or False:
In newborns, medullary cavities and all spongy bone contain red marrow.
true
True or False:
In adults, red marrow is located in heads of femur and humerus.
true
True or false:
Yellow marrow can covert to red, if person becomes anemic.
true
What are bone markings?
sites of muscle, ligament, and tendon attachment on external surfaces.
Are bone markings involved in joint formation and conduits for blood vessels and nerves?
Yes
What are the 3 types of bone markings:
projection: outward bulge of bone
depression: bowel or groove-like cut-out that serves as passageways for nerves/vessels
opening: hole/canal in bone acts like passageways for nerves/vessels.
What are the 5 major cell types?
osteogenic cells
osteoblasts
osteocytes
bone-lining cells
osteoclasts
what are osteogenic cells?
mitotically active stem cells in periosteum and endosteum
when stimulated what do osteogenic cells become?
they differentiate into osteoblasts or bone-lining cells
what are osteoblasts
bone-forming cells that secrete unmineralized bone matrix called osteiod
what is made up of collagen and calcium-binding proteins
osteoid
true or false
collagen makes up 90% of bone protein
true
what are osteocytes
mature bone cells in lacunae that no longer divide
what do osteocytes maintain?
they maintain bone matrix and act as stress or strain sensors
what are osteoclasts?
cells that destroy bone
what are bone-lining cells?
flat cells on bone surfaces believed to also help maintain matrix (along with osteocytes)
periosteal cells
on external bone surface, lining cells are called
endosteal cells
on internal bone surfaces is called
what are osteoclasts
giant, multinucleated cells that finction in bone resorption (breakdown of bone)
resorption bays
where are osteoclasts located at when active?
compact bone
What is also called a lamellar bone?
one of the 3 things a compact bone consists of
osten (haversian system)
one of the 3 things a compact bone consists of
canals and canaliculi
one of the 3 things a compact bone consists of
interstitial and circumferential lamellae
what is an osteon?
structural unit of compact bone