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Kidneys
Filter blood to remove metabolic wastes.
Regulate fluid, electrolyte, and acid-base balance.
Ureters
Two slender, muscular tubes (about 25–30 cm long)
* Transport urine from the kidneys to the urinary bladder via peristaltic waves of smooth muscle contraction.
Urinary Bladder
Temporarily stores urine (holding up to 700–800 mL).
Contracts to expel urine during micturition (urination).
hollow, distensible, muscular sac situated in the pelvic cavity,
Urethra
single thin-walled muscular tube leading from the bladder floor to the exterior of the body.
Drains urine from the bladder to be excreted out of the body.
In males, it also serves as the passageway for semen.
What are Normal Constituents of Urine?
Creatinine
Uric Acid
Electrolytes/Ions
Urochrome
What Should NOT be Found in Urine?
Glucose
Proteins/Albumin
Red Blood Cells
White Blood Cells
Bile Pigments / Bilirubin
Ketones
Microorganisms
Muscle Type of Internal Urethral Sphincter
Smooth muscle
(Involuntary control by the autonomic nervous system).
Internal Urethral Sphincter Location in Females
at the bladder neck (where the bladder connects to the urethra).
Location in Males Internal Urethral Sphincter
bladder neck, superior to the prostate gland.
Muscle Type External Urethral Sphincter
Skeletal muscle
(Voluntary control by the somatic nervous system).
External Urethral Sphincter Location in Females
Located inferiorly, where the urethra passes through the deep perineal pouch/urogenital diaphragm
External Urethral Sphincter Location in Males
Located inferior to the prostate gland, surrounding the membranous urethra.
Mucosa of bladder wall
transitional epithelium
Submucosa of bladder wall
rregular connective tissue containing blood vessels, lymphatic vessels, and nerves.
3. Muscularis in bladder wall
Composed of three interweaving layers of smooth muscle fibers running in
longitudinal,
circular,
oblique directions.
Serosa of bladder wall
superior surface is covered by parietal peritoneum
rest is covered by loose connective tissue
function of mucosa in bladder wall
Allows the bladder to stretch and flatten out as it fills with urine without tearing.
It also acts as a barrier to prevent urine from leaking into deeper tissues.
function of submucosa in bladder wall
Supports the mucosa and connects it to the underlying muscular layer.
function of muscularis in bladder wall
Contracts forcefully during micturition (urination) to expel urine from the bladder into the urethra.
function of Serosa in bladder wall
Anchors the bladder in place within the pelvic cavity and protects the organ.
What is the muscle within the bladder called?
detrusor muscle.
In males, what gland is found inferior to the bladder?
prostate gland
In females, how does the bladder relate to the uterus?
located anterior and inferior to the uterus
as bladder fills what receptors in the walls are activated
stretch receptors
the stretch receptors send sensory impulses that travel to which muscle
detrusor muscle of the bladder causing contraction causing to empty
what do we contract to override the micturition reflex
by contracting the external urethral sphincter
Mucosa of urterus
Composed of transitional epithelium
Muscularis of ureters
two layers of smooth muscle:
inner longitudinal layer
outer circular layer
Adventitia of ureters
loose fibrous connective tissue containing blood vessels, lymphatic vessels, and nerves.
Mucosa of urterus function
Distensibility: Allows the ureter to stretch and expand as urine passes through.
Protection: Acts as a chemical barrier
Mucosa of Muscularis function
Peristalsis: Propels urine toward the bladder via active, rhythmic muscular contractions.
Mucosa of Adventitia function
Anchoring: Blends with the surrounding connective tissues to anchor the ureters securely in place along the posterior abdominal wall.
Where are the kidneys located?
upper abdominal area, positioned against the back body wall.
kidneys secrete what hormone
erythropoietin (EPO)
-stimulate the bone marrow to produce red blood cells
kidneys secret what enzyme
renin which plays a role in
-the renin-angiotensin-aldosterone system (RAAS). This helps regulate blood pressure.
kidneys participate in the activation of vitamin
vitamin D (converting it into calcitriol)
affects calcium and phosphate absorption in the intestines, maintaining healthy bones and teeth.
Renal Capsule
fibrous connective tissue
Protects the kidney from trauma and physical injury.
arrier against the spread of local infections into the kidney tissue
Renal Hilum
slit or indentation on the concave curved border of the kidney.
Serves as the structural "gateway" or entry/exit point for the renal artery, renal vein, nerves, lymphatic vessels, and the ureter.
Renal Cortex
light-colored, granular superficial region of the kidney located directly beneath the capsule.
Contains the filtering units of the kidney
where blood filtration begins.
Renal Column
Anchors the cortex securely
safe pathway for blood vessels
(Renal Pyramid)
Contains the collecting ducts and loops of Henle
Striated in appearance, it is responsible for concentrating urine and funneling it toward the kidney's center via the pyramid tips (papillae).
Minor Calyx
Collects urine continuously draining from a single renal pyramid.
Major Calyx:
Funnels urine from multiple minor calyces down into the renal pelvis.
Renal Pelvis
large, flat, funnel-shaped cavity located deep within the renal sinus,
as a centralized collection basin that receives all urine from the calyces and channels it directly out into the ureter.
What structures pass through the hilum?
VAU
Renal Vein:
Renal Artery:
Ureter
Lymphatic Vessels
Nerves