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hisology
study of tissues
Tissues
group of cells that are similar in structure and finction
epithelial tissue
Linings and coverings
Epitheial layers: simple
one layer
Epitheial layers: stratified
more than one layer
Epitheial layers: pseudostraitifed
- 1 layer that appears to be many layers (only in trachea)
- has protective cilia covreed in mucos to protect lungs.
Epitheial cellular shape: Squamous
irregular/flat
Epitheial cellular shape: cubidal
box like
Epitheial cellular shape: columnar
rectangular
Connective tissue
living cells surrounded by a non-living matrix (supporting and binding)
Connective tissue Ground Substance
Glycoproteins in extracellular space, sticky but not permanent
Connective tissue fibers
provide support
collagen fibers, elastic fibers, reticular fibers
permanent
CT fiber types: Areolar
light packing material, looks like thin random lines
what firms/loosens skin
CT fiber types: Adipose
storage, insulaton, protection
made up of lipids (fats)
soap suds
CT fiber types: Recticular
network of fibers loose in matrix
shapes the soft internal organs
tree branches
CT fiber types: blood
transport repiratory gasses, nutrients, and waste
lots of tiny circles, semi organized
Muscle tissue
A body tissue that contracts or shortens, making body parts move.
Muscle Tissue: Skeletal
attached to bones, moves body, well organized, most common
Muscle Tissue: Cardiac
walls of the heart, moves blood
Muscle Tissue: Smooth
walls of hollow organs, move substances
Nervous tissue
specialized to conduct impluses for control and comunication
Nervous tissue cell types
Nuerons
Neuroglia
Integument (skin) layers
epidermis, dermis
Epidermis
thin outer layer, stratified squamous
Epidermis layers (deep to superficial)
stratum basale
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum
stratum basale
deepest layer of epidermis
area of fast mitosis
keeps water in
stratum spinosum
thickest
majority of the cell's life
stratum granulosum
where cells slow down till they die
stratum lucidum
optional
thin layer of dead cells
callus
stratum corneum
many layers of dead cells
Dermis
dense lower layer of the skin
iregular connective tissue
Dermis Layers: Papillary Layer
upper thin layer
dermapapill
dermapapill
what creates fingerprints, projections that create a pattern
Dermis layers: Recticular Layer
80% of dermin
orgin of appendages
Sebaceous (oil) glands
cells secrete sebum to act as lubricant for protection
everywhere but palms and soles
empties into hair follicles
sudoriferous (sweat) glands
secreate fluid containing waste
Eccrine sweat glands
respond primarily to elevated body temperature/ react to temp
Apocrine sweat glands
found in axillary and urogenital regions (stinks)
Hair
everywhere but palms of hands, soles of feet, nipples, lips, parts of external genitalia; root and shaft
arrector pili muscle
smooth muscle, attached at the base and contract to raise the hair and results in goosbumps
1st degree burn
damage to epidermis
2nd degree burn
damage to epidermis and upper dermis
get blister
3rd degree burn
epidermis and dermis destroyed
body never heals
Cutaneous membrane
skin, only dry membrane
mucous membrane
wet membrane
lines the cavities that open up to the exterior
serous membrane (serosa)
secreates fluid (lubricant, nutrition) aka WD-40
line closed body cavities
coverns organs
Parietal layer- outer
Visceral layer- inner
Pleura
lung serous membrane
Peritoneum
abdominal serous membrane
Pericardium
heart serous membrane
epithelial special characteristics: apical
the top surface, microvilli or cilia, inverted, avascular, regenerative
epithelial special characteristics: basal
bottom surface, adhesive, filters and supports
Gland
One or more cells that makes and secretes an aqueous fluid called a secretion
Endocrine
ductless, screte into blood
Exocrine
secrete into the ducts, external
Connective tissue characteristic
all derived from same embryonic tissue: mesenchyme
connective tissue proper
fibroblast
Cartlidge
chondroblast
Bone
osteoblast
blood
hematopoletic
dense regular connective tissue
parallel collagen fibers, ex: knee
dense irregular connective tissue
criss-cross collagen fibers, ex:skin
elastic connective tissue
stretchy and recoling tissue
Cartilage
tough, flexible, no nerves, avascular, surrounded by perichondrium
Hyaline
the most common cartilage that has collagen fibers, glassy, support, articular
elastic cartilage
rare cartilage, elastic fibers, strength and stretch, ex: ears, epiglattis
Bone
osseous tissue, support and protect
Blood
Matrix=blood plasma
transport
Marfans Syndrome
An inherited disorder that affects connective tissue, lack of elastic fibers, loose joints and long limbs
Steps of tissue repair: inflamation
control/minimize and respond to damage
clean up to prepare, macrophager
Steps of tissue repair: organization
resore blood supply
new capillaries bud
macrophager removes clots
Steps of tissue repair: Regeneration/ fibrosis
surface regenerates
scab falls off
scar tissues matures
leaves skin thicker in that area
Factors that influence repair
tissue type
blood suply level
type of injury, treatment,care
state of health
age
nutrition
Tissue changes that come with age
Epithelia: thins, easier to tear
Collagen: declines, repair is less efficient
Circulation declines
Carcinogen
substances that can lead to cancer
onceogenes
genes that make someone more prone to cancer
proto-oncogens
the un activated oncogenes
tumor suppressor genes
kill cancer cells
dedifferentiation
a specialized cell that tries to revert back into a stem cell
Neoplasm
newly discovered cancer growth
benign
local, encapsulated
malignant
spread, and metastasize
Dx- cancer
biopsy- see how severe
MRI/CT scan- checks size
RX- cancer
surgery, radiation, drugs
Keratinocytes
keeps water in, waxy
Melanocytes
melanin, deepest layer, protects against UV
Langerhan’s cells
1st layer, eat any “parasites, it is part of the immune system
Merkel cells
few in numbers, creates some sensory nerve endings/touch receptors
Striae
stretch marks
Cyanosis
blueish color, poor oxygenation
Erythema
redness, fever, allergy, blushing
Pale
palor, emotional stress, anemia, hypotension
Jaundice
yellow/liver disease
Bronzing
hypoaorenalism, addisons disease
Bruises
black and blue, hematation
Cerominous glands
modified apocrine glands that secrete cerumen
(ear wax)
Mammary gland
modified sweat glands, secrete milk
Whiteheads
pore clogged, beneath the surface
blackheads
sebum oxidizes, at the surface
Acne
inflamation of oil glands
Seborrhea
overactive glands