Monohybrid crossing and testcross experiments (DONE) week 10

EXAM #3

Describe the patterns in a human pedigree (family tree) indicating that a trait of medical interest is A(n)- Autosomal Recessive genetic disorder

• Both sexes equally affected

• traits can skip generations

• carrier parents

• clustering appear among siblings rather vertically across generation

Describe the patterns in a human pedigree (family tree) indicating that a trait of medical interest is A(n)- Autosomal Dominant genetic disorder

• trait appears in every generation

• both males and females are equally affected

• at least one affected parent

• no skipping generations

Describe the patterns in a human pedigree (family tree) indicating that a trait of medical interest is A(n)- X-Linked Recessive genetic disorder

• Trait is more common in males

• carrier females can pass to children

• trait can skip generations

• affected males do not pass trait to sons but all daughters of affected males are carriers

Describe the patterns in a human pedigree (family tree) indicating that a trait of medical interest is A(n)- X-Linked Dominants genetic disorder

• traits appear in every generation

• both sexes are affected

• all daughters of affected males are affected

• affected females transmit the trait to ~50% of children

Describe the patterns in a human pedigree (family tree) indicating that a trait of medical interest is A(n)- Cytoplasmically inherited (mitochondrial genome-related) genetic disorder

• maternal inheritance only (Mother to all children)

• both sexes affected

• No father-to-child transmission

• variable severity due to heteroplasmy