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Connective tissue general information
- Most abundant tissue in the human body
- Composed of large amount of intercellular material consisting of ground substance and fibers and relatively few cells
- Most (two exceptions) types of CT are poorly vascularized
4 major types of connective tissue
CT proper, Blood, cartilage, and bone
Connective Tissue composed of :
rich thick intracellular material (matrix) and few loose cells
Intercellular material (matrix)
Composed of ground substance and fibers
CT function
- protection
- supports and bind other tissues together
-provides metabolic needs of other tissues
extracellular material- ground substance
-Serves as a pathway for the transport and exchange of nutrients and waste products between the blood and the tissue cells
- gel like homogenous material produced by CT cells
Different types of fibers
Collagenous, elastic, and reticular
Collagenous fiber
mechanical strength and durability, most abundant protein in body
elastic
-composed of the protein elastin
-capable of stretching and recoiling like a rubber band
Reticular
support amd organize
made of reticulum, thin threads form a delicate network; mesh-like
cell types in connective tissue
fibroblast, fat cell, macrophage, plasma cell, and mast cells
fibroblast
•Most abundant cell
•Star or elongated cell that produces & maintains CT fibers
Fat cell (Adipocytes)
stores fats (lipids)
Macrophage (phagocytes)
Engulf bacteria and debris
Plasma cells
produce antibodies to fight infections
Mast cells
immune response cell, produce histamine. Affect permeability of blood vessels
4 types of CT proper
- Loose/Areolar
-Dense (regular and irregular)
-Elastic tissue
-Adipose
loose (areolar) connective tissue proper appearance
•Abundant intercellular material
•Few cells and scattered fibers
•Very vascular (lots of blood vessels)
Loose areolar CT proper location
Distributed throughout the body:
-Packing material around organs
-Surrounds muscle & blood vessels
-binds skin to underlying muscle
Dense CT proper appearance
•Large number of collagenous fibers packed closely together
•Poor blood supply
•Strong yet flexible
Dense irregular CT proper
fibers are randomly arranged fibers
Dense regular CT proper
fibers are neatly arranged parallel to one another
Dense CT proper location
- Ligaments and tendons (regular)
-Outer covering of the eye (irregular)
Elastic CT proper composition
•Contains many irregularly arranged elastic fibers
•Can be easily stretched and returns to original size
Elastic CT proper location
- walls of arteries
-larynx
-trachea
-bronchi
Adipose CT proper composition
composed of fat cells filled with lipid
Adipose CT proper location
- throughout body
ex; hypodermis (sub-cutaneous tissue)
Cartilage
Composed of:
-.Intercellular material - Chondroitin Sulfate Semisolid, gelatin-like substance
-Cells (chondrocytes)
These cells live in a small space called lacunae
-.Fibers – various types
Cartilage other special characteristics
Perichondrium: Though outer CT covering
Avascular: receives nutrients by diffusion, heals slowly