Blood groups

everyone’s blood cells express unique _________

antigens

sometimes regardless of exposure people can develop _______ to RBC antigens that they do not have

antibodies

All B type cats contain _________ levels of antibodies against ____________

• clinically relevant

• type A blood

what other reasons besides natural formation to RBC antibodies form?

• transfusions

• exposure to infectious agents

• idiopathic

• neonatal isoerythorlysis

what are the most clinically relevant canine RBC group

DEA 1

most dogs do not have _______ levels of naturally occurring antibodies

clinically relevant

almost ______ of all dogs in the US are DEA 1 positive

half

grayhounds are the ideal blood donor because they are often _______

DEA 1 negative

what are the 3 major blood types in cats

• type A

• type B

• type AB

most DSH and DLH cats are ________ while purebreds are mostly __________

• type A

• type B

utilizing species specific reagents to cause a visible reaction is known as ___________

blood typing

crossmatching is generally used to prevent what?

acute transfusion reactions

a major crossmatch is done with ________ and __________

• donor cells

• patient serum

a minor crossmatch is done with _______ and __________

• donor serum

• patient cells

a major mismatch determines if your_______ has antibodies to ___________

• patient

• donor RBC

a minor mismatch determines weather your_______ has antibodies to ______

• donor

• patients RBCs

you would only do a major crossmatch is only giving __________

packed RBCs

a delayed transfusion reaction will take place __________ after

4-10 days

most dogs with _______can be given blood without crossmatching

no transfusion record

before giving a transfusion cats must be _______

cross matched

in horses it is possible during birth for the _______ to develop antibodies against the _______

• mom

• foal

when mares develop antigens against foals it is called ___________

neonatal isoerytholysis

NI(neonatal isoerythrolysis) can be caused due to _____________or a previous transfusion

retroplacental hemorrhage

foals are exposed to these maternal RBC antibodies through _______

colostrum

clinical signs of NI foals are?

• weakness

• dyspnea

• icterus

laboratory findings of NI foals are?

• increased MCV

• increased MCHC

• bilirubbenima