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Substution and Elimination

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6 Terms

1
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Polar aprotic solvent

Acetone, DMSO, DMF, acetonitrile and THF

2
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Strong base and strong nucelophile

OH, OME, OEt

3
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Strong nucelophiile and weak bases

Halides (I, Br, Cl) , CN , OAc, N3 and SR

4
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Weak Base and Weak nucelophile

H20, Ethanol and methanol (Meoh)

5
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Strong base / Weak nucelophile

Kotbu and LDA

6
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Good leaving group

Otf, Ots, Oms, I , Br, Cl