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bacterial endotoxins cause macrophages to release
cytokines (IL-1, TNF, and nitric oxide
macrophages releasing cytokines (IL-1, TNF, and nitric oxide creates
systemic inflammatory response system
the systemic inflammatory response system effects are
tachycardia, tachypnea, fever, and leukocytosis
SIRS and bacteremia causes
sepsis
sepsis causes 1st sign
vasodilation, hypotension, tissue inflammation, tissue hypoperfusion (warm shock)
the cold shock of sepsis is myocardial depression, worsening tissue hypoperfusion that will lead to
multiple organ failure
the immune system overreaction during septic shock causes
vasodilation, leaky vessels, poor perfusion and it CANNOT COMPENSATE