pchem: pKa, pKb, pH

pKa of H2O (water)

14

pKa of R-COOH (carboxylic acid)

4

pKa of R-SO3H (sulfonic acid)

~1

pKa of CF3-COOH (trifluoroacetic acid)

~1

pKa of Ar-SO3H (sulfonic acid)

~1

pKa of R-OH (alcohol/hydroxyl)

14

pKa of Ph-OH (phenol)

10

pKa of R-SH (thiol)

~11

pKb of NH3 (ammonia)

5

pKa of Ar-COOH (carboxylic acid)

4

pKb of R-NH2 (primary amine)

5

pKb of R2-NH (secondary amine)

5

pKb of R3-N (tertiary amine)

5

pKb of C3H4N2 (imidazole)

7

pKb of C5H5N (pyridine)

~9

pKb of C6H5NH2 (aniline)

~10

pKb of DBU (amidine base)

~2

pKb of CH5N3 (guanidine)

~1

pKb of C4H5N (pyrrole)

14

pKb of C4H9N (pyrrolidine)

~3

pKb of purine

4,5,~12 (3 basic centers)

pH of the stomach

1

pH of the intestine (duodenum)

5

pH of the intestine (lower ileum)

8

pH of circulating fluids (plasma, CSF)

7