Lecture Exam 1!

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172 Terms

1
what two hormones are from the posterior pituitary?
==ADH== (antidiuretic hormone) and ==oxytocin==
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2
hypothalamus controls the two parts of pituitary differently. how?
  • uses neurons to control posterior

  • uses hormones to control anterior

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3
sleepy hormone that ==pineal gland== makes?
melatonin
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4

what hormones do your thyroid gland make?

t3, t4, and calcitonin

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5

inside thyroid gland- what cell makes t3 and t4?

folicular cells

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6
t3 and t4 increase..
metabolism
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7

what cells make calcitonin inside thyroid gland?

parafollicular (c cells)

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8
calcitonin
lowers blood calcium levels if it’s too high
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9
PTH (parathyroid hormone)
increases blood calcium levels if it’s too low
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10

PTH goes to kidneys, sets calcitriol (vit D)

to retain sodium

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11

3 parts of the cortex?

zona glomerulosa, zona fascilata, zona reticularis

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12
2 big things coming out of adrenal medulla?
epinephrine and norepinephrine (aka adrenaline)
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13
what is coming out of zona reticularis?
estrogen and testosterone
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14
what is main thing coming out of zona fasiculata?
cortisol (increase blood sugar levels for jolt of ATP)
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15
zona glomerulosa secretes..
aldosterone (regualates electrolyte balacne in kidneys to retain sodium keep in body)
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16

pancreas is

exocrine and ednocrine

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17

the 5 cells in pancreas islets of langerhans:

alpha cells

beta cells

delta cells

pp cells (f cells)

G cells

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18
alpha cells make what hormone
glucagon
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19
beta cells make what hormone
insulin
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20

what does glucagon do?

released between meals to raise the blood glucose level. this comes from the liver bec the liver stores sugar.

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21

delta cells make

somatostatin— partially suppresses secretion of glucagon and insulin

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22

what does insulin do?

secreted during and after a meal; stimulates cells to absorb these nutrients and store or metabolize them lowering blood glucose levels; cells take some of that sugar when levels are lowered

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23
what 2 places makes somatostatin?
pancreas and hypothalamus
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24

What does gastrin do?

stimulates stomach acid (enzymes and hydrochloric acid); “wakes up the stomach”

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25

Pancreatic polypeptide does what

inhibits the gallbladder; conserves the bile “tells polypeptide not to contract”

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26
How do target cells know a hormone is out there?
Binding receptor (they are all specific for one thing. ) ex- insulin receptor only for insulin
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27
Up and down regulation
Up refers to how many receptors

Down refers to numbers reduced receptors

Important because of strong and weak responses
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28

Antagonistic

one hormone opposes the action of another (for ex- insulin lowers blood glucose and glucagon raises it)

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29
Synergist
Hormones released at same time bec working together for one specific thing (fsh and testosterone to maximize sperm production)
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30

Permissive

2 Working together for same process but one released first and next released later on to enhance

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31
What are some of the differences between type one and type 2
Type 2 reversible; more common; cells don’t respond to insulin so no sugar to cells and stuck in blood

Type 1 genetic; insulin shots because don’t have enough insulin problem with beta cells don’t make any
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32
Parts of stomach
Body, pyloric region, fudus, cardiac
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33

5 cells in gastric glands

Mucous, regenerative, parietal, chief, enteroendocrine

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34
Mucous cells make
Mucous with little alkaline
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35
Mucous job?
Protection for epithelial cells from hydrochloride acid
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36
Regenerative stem cells
Mitosis magic
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37
chief cells
Make two enzymes- Pepsi oven gastric lipase
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38
Pepsinogen
Activated to become pepsin, protein breaking down enzyme
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39
Parietal cells make 3 things
Hcl, intrinsic factor, grehlin
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40
Grehlin
Hunger hormone
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41
What does intrinsic factor do
Help absorb b 12 in small intestine very efficient
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42
Hcl has five jobs
Activates pepsinogen to pepsin, liquify food to chyme,, converts f3 to f2, kills pathogens, activate lingual lipase
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43
Two starting ingredients to make hcl
Co2 and h2o (the one place where co2 is not a waste product)
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44
H2co3 needs an enzyme to drive reaction
Carbonicanhydrase
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45
Carbonic naturally splits into
Hydrogen and whatever is left over
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46
What’s a buffer
Regulate pH
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47
Hco3 is good buffer. Cell does not need bicarbonate ion. Goes to blood. What process is this?
Chloride shift
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48
Left free hydrogen in parietal cell. Second away from killing? What to do with hydrogen
use active transport to get hydrogen out to lumen of stomach. Named hydrogen potassium pump!
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49

Alkaline

Only in blood around stomach

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50
What causes around stomach to become slightly alkaline
Extra bicarbonates chucking out to make a lil more
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51

gap junctions

pores in cell membrane allow signaling molecules, nutrients, and electrolytes to move from cell to cell

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52

hormones are

chemical messengers that travel in the bloodstream to other tissues and organs

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53

exocrine glands

have ducts carry secretion to an epithelial surface of the mucosa of the digestive tract

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54

endocrine glands

No ducts; uses cardiovascular system; contain dense, fenestrated capillary networks which allows easy uptake of hormones into bloodstream

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55

the posterior lobe of the pituitary is part of the

brain

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56

the anterior lobe of the pituitary is _ from the brain.

separate

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57

neurohypophysis (posterior pituitary)

downgrowth from the brain

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58

adenohypophysis (anterior pituitary)

arises from hypophyseal pouch (outgrowth of pharynx)

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59

cellular respiration (how our cells make energy storage-ATP!) consists of

glycolysis (cytoplasm), Krebs (mitochondrial matrix), ETC (mitochondria)

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60

95% of our energy comes from

mitochondria

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61

nutrition is the

starting point and basis for all human form and function; the source of fuel that provides the energy for all biological work.

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62

metabolism is the

chemical changes that lie at the foundation of form and function; the summation of all catabolic and anabolic processes!!

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63

there are chemical reactions in us happening 24/7 and metabolism is the

sum of all these chemical reactions!

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64

anabolic

taking two small molecules and making bigger molecules; increases; inputs energy from ATP

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65

catabolic

big molecule broken into smaller pieces (breaks covalent bonds) which releases energy; cells collect the energy and store it as ATP

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66

glycolysis can be with or without

oxygen

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67

etc needs _ to work or else it shuts down.

oxygen

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68

for every sugar, krebs goes

twice!

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69

In anaerobic fermentation (respiration), the fate of pyruvate..

depends on oxygen availability

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70

anaerobic fermentation—

in absence of oxygen, the cell resorts to this one step reaction— NADH donates a pair of electrons to pyruvate reducing it to lactic acid which regenerates NAD+

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71

after glycolysis, the pyruvate slides into the mitochondria by __

diffusion! high concentration to low.

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72

total net yield from one sugar at the end of cellular respiration is

36 atp

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73

beta oxidation

catabolizes the fatty acid components in the mitochondrial matrix

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74

the hypothalamus regulates primitive functions of the body from

water balance and thermoregulation to sex drive and childbirth; many of its functions are carried out by the pituitary gland

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75

posterior pituitary does not make the hormones.. it only _ them.

stores

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76

the two hormones both stored and released by the posterior pituitary are

antidiuretic hormone (ADH) and oxytocin.

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77

what systems does the thymus play a role in?

endocrine, lymphatic, and immune

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78

the thymus is the site of

maturation of T cells

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79

the thyroid gland is the _ pure endocrine gland.

largest

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80

the thyroid follicles contain follicular cells which secrete

T3 and T4

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81

t3 and t4 increase

metabolism

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82

t4 is more _ while t3 is more _.

abundant; active

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83

parafollicular cells (c cells) secrete..

calcitonin

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84

calcitonin works to

decrease blood calcium levels (goes to osteoblasts for bone formation)

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85

thyroid makes more t4 but t3..

is stronger.

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86

the parathyroid glands (4 of them) secrete..

parathyroid hormone.

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87

what does parathyroid hormone do?

increases blood calcium levels > goes to osteoclasts (bone-dissolving)

this promotes the synthesis of calcitriol to tell kidneys to use the activation of vitamin D to increase absorption of calcium

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88

the adrenal glands sit

above each kidney.

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89

the adrenal glands secrete

epinephrine and norepinephrine (adrenaline)

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90

what are the 3 layers of the adrenal cortex from inside out?

zona reticularis, zona fasciculata, zona glomerulosa

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91

explain zona glomerulosa

the thin OUTER layer; secretes ALDOSTERONE which regulates the body’s electrolyte balance (retain sodium and excrete potassium)

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92

explain zona fasciculata

the thick MIDDLE layer; responds to ACTH from pituitary; secretes glucocorticoids (CORTISOL) to increase blood sugar for a jolt of ATP!

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93

explain zona reticularis

the narrow INNER layer; secretes sex steroids (androgens and estrogen)

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94

the pancreas is 98% _ and 2% _ .

exocrine; endocrine

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95

The clumps of cells in the pancreas are called

islets of langerhans

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96

g cells secrete

gastrin

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97

pp cells (f cells) secrete

pancreatic polypeptide

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98

the kidney is the 2nd biggest _ organ.

multitasking

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99

the kidneys produce 85% of _

erythropoietin (stimulates bone marrow to produce RBCs)

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100

hyposecretion

(not enough) inadequate hormone release

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