SIADH (copy)

A condition where excessive antidiuretic hormone (ADH) is secreted from the pituitary gland, leading to excessive water retention and low sodium levels.

Syndrome of Antidiuretic Hormone (SIADH)

Causes of SIADH?

• Lung tumors (Small cell lung cancer)

• Head injuries

• Brain surgery

• Brain tumors

• Sepsis

• Medications

Medications that can cause SIADH?

• Dry anesthesia

• Carbamazepine (Tegretol)

• Thiazide diuretics

• Antidepressants

  • - ine’s

  • -pram’s

SIADH can cause water to be retained which results in what?

Dilutional hyponatremia

Fluid overload

What Pulmonary disorders are risk factors for SIADH?

• Viral PNA

• Bacterial PNA

What CNS disorders are risk factors for SIADH?

• Head trauma

• Brain tumors

What are Symptoms of SIADH when sodium is under 130?

Muscle cramps & weakness

Fatigue

Anorexia

Vomiting & abdominal cramps

Excessive thirst

What are Symptoms of SIADH when sodium is under 120?

Twitching & seizures

Lethargy

Headache

Confusion

Cerebral edema

Increased body weight

What would Pharmacological treatments would a Nurse use for this treatment?

• Vasopressin receptor antagonist

  • Tolvaptan

  • Conivaptan

• 3% saline

  • Correct the sodium deficit 

• Loop diuretic (Furosemide)

  • Decreases fluid overflow

  • (DO NOT use Thiazides)

• Manitol

  • Decreases fluid overflow

  • Loop diuretics are preferred over this

What would a Nurse implement regarding this condition?

• Fluid restriction

• Seizure precautions

What would a Nurse Monitor regarding this condition?

• I&O’s

• L.O.C.

• Daily weights

If left untreated what could happen?

• Death

• Coma