Common lymphoid progenitor cells & B-cell development in adults

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Last updated 10:50 PM on 2/21/25
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4 Terms

1
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What can common lymphoid progenitor cells differentiate into?

NK cells, innate lymphoid cells, B cells, or T cells.

2
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What does binding of IL-7 promote in common lymphoid progenitor cells?

It promotes chromatin remodeling, allowing access to the immunoglobulin genes by the V(D)J recombinase.

3
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Where does B-cell development primarily occur in adults?

In the bone marrow, which also serves as the site for most hematopoiesis events.

4
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Where do B cells complete their development after beginning in the bone marrow?

B cells complete their development in the spleen after starting in the bone marrow.