Antimicrobial Agents for Periodontal Disease

Vocabulary flashcards related to antimicrobial agents for periodontal disease control.

Bacterial Plaque Biofilm

Prevention and control of periodontal disease depends in part on controlling bacterial oral plaque.

ADA and CDA

Organizations that provide additional guidance to oral healthcare providers in ensuring safety, quality, and efficacy of oral antimicrobials.

FDA

U.S. organization that contribute to ensuring safety, quality, and efficacy of oral antimicrobials.

Health Canada

Canadian organization that contribute to ensuring safety, quality, and efficacy of oral antimicrobials.

Adjunctive Antimicrobial Biofilm Control

Oral antimicrobial agents that have a definitive adjunctive benefit for reducing plaque biofilm and gingival inflammation beyond what is accomplished mechanically.

Antiseptic Agents

Kill or prevent propagation of plaque microorganisms.

Antibiotics

Inhibit or kill specific groups of bacteria, or modulate host inflammatory response.

Modifying Agents

Agents that alter the structure and/or metabolic activity of bacteria.

Antiadhesives

Interfere with the ability of bacteria to attach to acquired pellicle.

Antiseptics

Substances that inhibit the growth and development of microorganisms and demonstrate very little oral or systemic toxicity or microbial resistance.

Chlorhexidine gluconate (CHX)

Long viewed as the gold standard of therapeutic mouth rinses, available only by prescription.

Essential Oils

Components of plants that contain phenolic compounds that destroy microorganisms by compromising cell membrane and inhibiting enzyme activity.

Cetylpyridium chloride (CPC)

Mouth rinses that have antimicrobial properties.

Probiotics

Live microorganisms that have health benefits for the host when administered alone or in combination.

Controlled-Release Drug Delivery

Professionally placed intracrevicular devices that provide drug delivery for sustained periods of time.

Minimum Inhibitory Concentration (MIC)

Research measurement tool used for products to describe the lowest concentration of particular antimicrobial.

Minocycline Microspheres

Includes minocycline hydrochloride; available in North America as a dry powder; delivered via syringe-like handle to base of periodontal pocket; immediately adheres

Chlorhexidine Chip (PerioChip)

Biodegradable 4- to 5-mm hydrolyzed gelatin chip that incorporates 2.5 mg of chlorhexidine d-gluconate for insertion into pockets.

Doxycycline hyclate gel (ATRIDOX)

Consists of 10% doxycycline hyclate in a gel polymer

Subantimicrobial Systemic Dose

Administration of a reduced dose of a drug for purposes other than elimination of a pathogenic organism (host modulatory therapy).