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Necrosis of brain tissue results in
liquefaction degeneration
Enlargement of airspaces primarily caused by smoking can result in
emphysema
A 5 yo boy has CPK 300 times, pseudohypertrophy of the calf muscles and his prognosis is very poor, what is the diagnosis
Erb-Duchenne Muscular dystrophy
All of the following are characteristics of myasthenia gravis EXCEPT
primarily affects males
Reflex sympathetic dystrophy syndrome
causes anhydrosis (lack of sweating = sympathetics)
Wallerian degeneration of the axon occurs
distal to proximal
Where would you find the tophi of a gout patient
helix of the ear
A patient that presents with a “pannus” formation has
rheumatoid arthritis
What malignant tumor presents with a “sunburst” periosteal reaction
osteosarcoma
What is the MC primary malignancy of bone
multiple myeloma
What is the MC primary malignancy of bone in children
osteogenic sarcoma
What antibody activates the classic complimentary pathway, is the first response and largest immunoglobulin
IgM
The most clinically significant progression of Osteitis Deformans (Paget’s disease) is
osteosarcoma
The malignancy is found in a child’s kidney
Wilm’s tumor (nephroblastoma)
Krukenberg’s tumor
starts in GI tract and travels to ovaries
Longstanding Rheumatoid arthritis is termed
Felty’s syndrome
Prinzmetal angina is caused by
vasospasm of the coronary artery
The patient is very tall, has arachnodactyly, hyperextensibility, and aortic arch fragility. Which diagnosis would you choose
Marfan’s
Patients with a pheochromocytoma would
exhibit sympathetic rushes (neuroblastoma)
All of the following can cause pelvic inflammatory disease EXCEPT
anthracosis
One cell type changing to another is termed
metaplasia
Skip lesions are associated with what disease
regional enteritis (Crohn’s)
Multiple myeloma has which of the following periosteal responses
No response
Which leukocytes increases with a viral infection
lymphocytes
A increase in adrenocorticotropic hormone will cause a moon face, hirsutism, purple striae and a buffalo hump. What would be the best diagnosis
cushing’s (hyperadrenocorticoalism)
Hypo-adrenocorticotropic hormone can result in bronze skin and hypotension. This disorder is best known as
Addison’s
Stroke
FAST - Face drooping, Arm, Speech, Time
Monckeberg Atherosclerosis
calcified tunica media in medium sized arteries
MC location for an aortic aneurysm
abdominal
Abdominal aortic aneurism causes
anterior scalloping and ivory white vertebrae
Circle of Willis (anterior communicating) aneurysm is termed
Berry/saccular aneurysm
**Occurs in young males
Intermediate claudication
pain with activity but relieved with rest
Hypertension headaches occur in
occipital region
Types of Hypertension
Essential = >40 and idiopathic
Secondary = sodium retention and inc peripheral resistance
Benign = earliest phase
Malignant = papilledema, retinal hemorrhages, exudates
BP - 200/150 mmHg
Patent dutus arteriosus
congenital failure of closure btw pulmonary artery and aorta
Tetralogy of Fallot (DRIP)
Dextrorotation of aorta (rotated to right)
Right ventricular hypertrophy
Intraventricular septal defect
Pulmonary artery stenosis
Rheumatic fever effects what two valves
mitral and aortic
Frank vs Occult
frank - blood in urine
occult - blood in stool
Pernicious anemia can be caused by what two vitamin deficiencies
B12 and B9
Prinzmetal angina occurs
at rest
Esophageal varices is be caused by
portal hypertension
Mallory Weiss
hemorrhage due to alcoholism
Hematomesis
throwing up blood
Cancer of the stomach typically occurs where
greater curvature
Steatorrhea
fatty stool
Emphysema
pink puffer
Lung cancer
clubbing nails
Goodpasture’s syndrome
rapid progressive glomerulonephritis and necrotizing hemorrhagic interstitial pneumonia of basement membrane
Hypospadias
urethra defect on VENTRAL surface
Joint mice in synovial fluid can be due to
osteoarthritis
What condition causes atrophy of the villi with resultant malabsorption
celiac sprue
Parasitic infections show an increase in what cell
eosinophils
Which condition is characterized by the presence of a 45X karyotype
Turner syndrome
Which vitamin is the most important in would healing
vitamin C
T-helper cells are seen in which hypersensitivity reaction
type IV
What is the pathognomonic of parkinson’s
lewy bodies
People with parkinson’s are deficient in
Dopamine
What is a condition associated with kidney stones
hyperparathyroidism
With this form of hepatitis you can be cured and not become a carrier
Hepatitis C
Which disease are characteristic Bence Jones proteins
multiple myeloma
Krukenburg’s tumor is of what organ
ovary
What is the MC benign brain tumor
meningioma
What causes demyelination of peripheral nerves
Guillain Barre syndrome
What causes demyelination of the CNS
multiple sclerosis
Which phase is NOT consistent with phases of Paget’s disease
predominance of osteoclastic activity in 2nd phase
Cervical cancer is most likely associated with
HPV
Involuntary movements are caused by a lesion of
basal ganglia
Which disease presents with fever, Koplik spots, and a red papular rash
rubeola (measles)
Brown lung disease is also called
byssinosis
Mask-like face, claw-like fingers, hypertension and fibrosis of the esophagus are characteristics of what disease
Scleroderma (CREST syndrome)
**CREST = Calcinosis, Raynaud’s, Esophageal dysfunction, Sclerodactyly, Telangiectasia
Avascular necrosis of the lunate carbal bone is called
Kienbock’s disease
A fracture of the distal radius with anterior displacement of the distal fragment is known as
Smith fracture
Hyperuricemia and monosodium urate crystals are usually associated with which disease
gout
What is a major cause of dwarfism
achondroplasia
An ivory white vertebra with obvious bone enlargement and cortical thickening leads one towards the diagnosis of
Osteitis deformans (Paget’s)
Pyknosis is characterized by nuclear
condensation
Calcification of the ALL and sparing of the disc spaces are two most important findings in
Diffuse Idiopathic Skeletal Hyperstosis
A pathological accumulation of air in airspaces would best be described as
emphysema
Hyperglycemia, acidosis, polydipsia are symptoms of
hypoinsulinism
Iron deficiency anemia MC presents itself on a laboratory blood test as
microcytic hypochromic
An excessive amount of cortisol is characteristic of
Cushing’s disease
In an eye exam a pupil that accommodates but has no pupillary reflex is called
Argyll Roberston pupil
Course, rhythmic tremors of the hands and tongue, stooped posture, expressionless face and slowness of the voluntary movements are characteristic of
Parkinson’s disease
Which disorder is most likely to be responsible for iron deficiency anemia in males
peptic ulcer
Which is not characteristic of Horner’s syndrome
dyspnea
Caseous necrosis is a form of necrosis unique to
TB
What two lung tumors are MC caused by smoking
squamous cell carcinoma
adenocarcinoma
Mature cells of atypical size, shape and organization are characteristic of
dysplasia
A pneumoconiosis characterized by an accumulation of iron dust in the lung is referred to
Siderosis
All of the following are findings with ankylosing spondylitis EXCEPT
Knife clasp syndrome
Exacerbations of hemolytic anemia when RBCs are exposed to oxidative stressors may be caused by deficiency of
vitamin E
Infection of pathogenic anaerobes of the saccharolytic group of genus clostridium causes
gas gangrene
Which of these conditions is characterized by T cell deficiency due to lack of development of the thymus, abnormality of heart and vessels, mouth, ears, palate
DiGeorge