Activity 1. Fundamentals of IUPAC Nomenclature

IUPAC Nomenclature

systematic naming of organic compounds

International Union of Pure and Applied Chemistry

meaning of IUPAC

prefix

General Formula of IUPAC Nomenclature
a.________ + b._________ + c.____________ + d._______________

a. = ?

parent

General Formula of IUPAC Nomenclature
a.________ + b._________ + c.____________ + d._______________

b. = ?

bond type

General Formula of IUPAC Nomenclature
a.________ + b._________ + c.____________ + d._______________

c. = ?

suffix

General Formula of IUPAC Nomenclature
a.________ + b._________ + c.____________ + d._______________

d. = ?

Substitutive

• The most commonly used operation in providing systematic names for organic compounds

• It substitutes one or more hydrogen atoms for another atom or group of atoms (e.g., functional groups).

• All fundamental rules for IUPAC nomenclature falls under this operation.

Additive

involves formal assembly of compounds from its component parts without any loss of any atoms or groups

hydro-

In additive, we add the prefix ___________ to the presence of H atoms in place of double bonds.

Perhydro-

In additive, we add the prefix ___________ if all double bonds were replaced by a hydrogen atom.

Subtractive

involves the removal of an atom, ion, or group and is made implicit in the name

-demethyl

This is the prefix used when you remove a methyl group

nor-

This is the prefix used when you remove a methyl group especially from a N-atom

deoxy-

This is the prefix used when you remove an oxygen group

dehydro

This is the prefix used when you remove a hydrogen

seco

This is the prefix used when you open a ring

conjunctive

rare form of nomenclature operation which involves the name of a compound from its components without assuming that a particular part serves as a substituent.

Replacement / “a”

exchange of an atom for another. It is also called “a” nomenclature because the prefixes always ends with “a”

oxygen

oxa = ?

sulfur

thia = ?

selenium

selena = ?

nitrogen

aza = ?

phosphorus

phospha = ?

silicon

sila = ?

Radicofunctional

• It involves adding the actual name of the functional group at the end and the component parts are named as radicals ending in “-yl”.

• This is commonly observed among common names of compounds

conjunctive

3-quinolineacetic acid

replacement

1-oxa-3-thiacyclohex-4-ene

substitutive

2-methylbutanoic acid

subtractive

norpinane

radicofunctional

isopropyl alcohol

additive

2,3,4,5-tetrahydrothiole

conjunctive

indole-1-propanoic acid

replacement

6,8-dithia-3,5-diazadecane

radicofunctional

tert-butyl chloride

substitutive

2-[2-(2-bromo)ethyl)butoxy]pentanal