prototype drugs unit 4

respiratory

compliance

stretchiness of lung

ventilation

air movement in and gas movement out

diffusion

net movement of molecules from an area of high concentration to low concentration

what controls respiration?

chemoreceptors and mechanical receptors

chemoreceptors

respond to changes in O₂, CO₂, and H⁺ in our arterial blood

mechanical receptors

detects mechanical forces (movement, tension, pressure) and affects respiratory rate and surfactant production

bronchodilators

a¹ and B² adrenergic agonists, leukotriene inhibitors, anticholinergics, and xanthines

short acting selective B₂ agonist

albuterol

short acting selective B₂ agonist

levalbuterol

long acting selective B₂ agonist

salmeterol

non selective a and B agonist

epinephrine

leukotriene inhibitor

Montelukast

anticholinergic

impatropium

xanthine

theophylline

theophylline therapeutic drug level

10 - 20 mcg/mL

oral glucocorticoidsteroid

prednisone

inhaled glucocorticoidsteroid

beclomethasone

inhaled glucocorticoid

fluticasone

parenteral glucocorticoidsteroid

dexamethasone

parenteral glucocorticoidsteroid

hydrocortisone

parenteral glucocorticoidsteroid

methylprednisolone

glucocorticoidsteroid suffix

-one

antihistamine

diphenhydramine

antihistamine

loratadine

oral decongestant

pseudoephedrine

inhaled decongestant

oxymetazoline

inhaled decongestant

mometasone

inhaled decongestant

phenylephrine

narcotic antitussive

codeine

narcotic antitussive

hydrocodone

non-narcotic antitussive

dextromethorphan

types of antitussives

narcotic and non-narcotic

expectorant

guaifenesin

mucolytic

acetylsteine

types of a¹ and B adrenergic agonists

selective B₂ and non-selective a and B

glucocorticoidsteroid routes

oral, inhaled, and parenteral