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what does DNA stand for
deoxyribonucleic acid
what does rna stand for
ribonucleic acid
dna nucleotide structure
nitrogenous base, deoxyribose sugar, phosphate group
rna nucleotide structure
nitrogenous base, ribose sugar, phosphate group
base names in DNA
adenine, thymine, cytosine, guanine
base names in RNA
adenine, uracil, cytosine, guanine
purines
adenine and guanine, double ring structure
pyrimidines
cytosine, thymine, uracil, single ring structure
how are h bonds formed
hydrogen donor and acceptor needed, donor usually a strong electronegative atom covalently bonded to a h atom, acceptor is an electronegative atom of neighbouring molecule or ion with a lone pair
meselson and stahl experiment for dna replication
grew a huge population of e coli on a n-15 growth medium, after centrifugation, the heavy dna appears as a low band, bacteria grown in n-15, transferred to a n-14 growth medium, bacteria allowed to replicate once, band appeared in the middle
semi conservative dna replication
dna helicase breaks h bonds between base pairs, double helix separates and unwinds, exposed polynucleotides attract free floating nucleotides which are activated by atp to form complementary base pairs, dna polymerase forms phosphodiester bonds between nucleotides, each new dna molecule contains one new and one old strand