generic, brand, class, moa, use, normal adult dose, contraindications, bbw
lisinopril
Prinivil, Zestril
lisinopril class
ACE inhibitor
lisinopril moa
inhibits conversion of angiotensin I to angiotensin II
lisinopril use
hypertension, heart failure
lisinopril dose
5-40 mg PO qD
lisinopril contraindications
pregnancy, angioedema
lisinopril bbw
do not use during pregnancy
amlodipine
Norvasc
amlodipine class
CCB
amlodipine moa
inhibits calcium ion influx into vascular smooth muscle and myocardium
amlodipine use
hypertension, heart failure
amlodipine dose
5-10 mg PO qD
amlodipine contraindications
none
amlodipine bbw
none
metoprolol
Lopressor, Toprol XL
metoprolol class
B1 blocker
metoprolol moa
selectively antagonizes beta-1 adrenergic receptors
metoprolol use
hypertension, angina, CV event prevention, migraine
metoprolol dose
50-100 mg PO BID or 50-200 m ER PO qD
metoprolol contraindications
sinus bradycardia, 2nd/3rd degree heart block, heart failure
metoprolol bbw
do not stop abruptly
losartan
Cozaar
losartan class
ARB
losartan moa
selectively antagonizes angiotensin II receptors
losartan use
hypertension, diabetic neuropathy, stroke prevention
losartan dose
50-100 mg PO qD
losartan contraindications
pregnancy
losartan bbw
do not use during pregnancy
carvedilol
Coreg, Coreg CR
carvedilol class
Selective alpha and non-selective beta-adrenergic blocker
carvedilol moa
Selectively antagonizes alpha 1 adrenergic receptors and non-selectively antagonizes beta 1 and beta 2 adrenergic receptors
carvedilol use
hypertension, heart failure
carvedilol dose
6.25-25 mg PO BID
carvedilol contraindications
bradycardia, asthma, sick sinus syndrome, 2nd/3rd degree heart block
carvedilol bbw
none
atenolol
Tenormin
atenolol class
selective beta 1 blocker
atenolol moa
selectively antagonizes beta-1 adrenergic receptors
atenolol use
hypertension, angina, post MI CV event prevention
atenolol dose
25-100 mg PO qD
atenolol contraindications
sinus bradycardia, 2nd/3rd degree heart block, heart failure
atenolol bbw
do not stop abruptly
propranolol
Inderal, Inderal LA
propranolol class
nonselective beta blocker
propranolol moa
non-selectively antagonizes beta-1 and beta-2 adrenergic receptors
propranolol use
hypertension, angina, arrhythmias, CV event prevention
propranolol dose
80-240 mg qD divided BID/TID or ER
propranolol contraindications
Asthma, sinus bradycardia, AV block
propranolol bbw
do not stop abruptly
diltiazem
Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Dilacor XR, Taztia XT, Tiazac
diltiazem class
CCB
diltiazem moa
inhibits calcium ion influx into vascular smooth muscle and myocardium
diltiazem use
hypertension, angina, a fib
diltiazem dose
30-90 mg PO QID, or 120-480 mg ER PO qD
diltiazem contraindications
sick sinus syndrome, 2nd/3rd degree heart block, SBP <90
diltiazem bbw
none
valsartan
Diovan
valsartan class
ARB
valsartan moa
selectively antagonizes angiotensin II receptors
valsartan use
hypertension, heart failure
valsartan dose
80-320 mg PO qD
valsartan contraindications
pregnancy, age <60
valsartan bbw
not to be used during pregnancy
benazepril
Lotensin
benazepril class
ACE inhibitor
benazepril moa
inhibits conversion of angiotensin I to angiotensin II
benazepril use
hypertension, heart failure
benazepril dose
5-10 mg PO qD
benazepril contraindications
pregnancy, angioedema
benazepril bbw
not to be used during pregnancy
nifedipine
Adilat CC, Nifedical. XL, Procardia, Procardia XL
nifedipine class
CCB
nifedipine moa
inhibits calcium ion influx into vascular smooth muscle and myocardium
nifedipine use
angina, hypertension
nifedipine dose
10-20 mg PO TID or 30-90 mg ER PO qD
nifedipine contraindications
hypertensive crisis
nifedipine bbw
none
enalapril
Vasotec
enalapril class
ACE inhibitor
enalapril moa
inhibits conversion of angiotensin I to angiotensin II
enalapril use
hypertension, heart failure
enalapril dose
5-40 mg divided qD/BID
enalapril contraindications
pregnancy, angioedema
enalapril bbw
not to be used during pregnancy
verapamil
Calan, Calan SR, Verelan, Verelan PM
verapamil class
CCB
verapamil moa
inhibits calcium ion influx into vascular smooth muscle and myocardium
verapamil use
hypertension, angina, anti-arrhythmia
verapamil dose
80-120 mg PO TID or 180 mg ER PO qD
verapamil contraindications
left ventricular dysfunction, sick sinus syn, SBP <90, 2nd/3rd degree AV block
verapamil bbw
none
ramipril
Altace
ramipril class
ACE inhibitor
ramipril moa
inhibits angiotensin converting enzyme, preventing conversion of angiotensin I to angiotensin II
ramipril use
hypertension, heart failure, CV event prevention
ramipril dose
2.5-20 mg divided qD or BID
ramipril contraindications
angioedema, pregnancy
ramipril bbw
not to be used during pregnancy
irbesartan
Avapro
irbesartan class
ARB