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what is the pathway of conductivity in the heart? (5)
- sinoatrial node
- atrioventricular node
- His bundle
- either right or left bundles
- Purkinje fibres
what is the effect of parasympathetic innervation of SA node? (3)
- acetylcholine acts of M2 muscarinic receptors at SA node
- lengthens the interval between pacemaker potentials
- slows heart rate
which nerve delivers the parasympathetic innervation of the heart?
vagus nerve (CNX)
what is the effect of sympathetic innervation of the SA node? (3)
- noradrenaline acts on B1 adrenoceptors
- shortens interval between pacemaker potentials by making it steeper
- increases heart rate
which nerve supplies sympathetic innervation to the heart?
sympathetic cardiac nerves
what is the intrinsic heart rate without autonomic inputs?
100bpm
what is the actual normal resting rate and why?
60bpm - parasympathetic system dominates at rest
what is initial increase in heart rate caused by?
decrease in parasympathetic outflow
what is further increase in heart rate caused by?
increase in sympathetic outflow