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examples of long bones
femur, humerus, ulna, radius, clavicle, metacarpals, phalanges
examples of short bones
carpals, tarsals
examples of flat bones
scapula, ribs, sternum
example of a pneumatized bone
ethmoid bone
example of a sesamoid bone
patella
sutural (wormian) bone
projection growing into the suture- found within the sutures of the skull
examples of irregular bones
vertebrae, temporal bone
canaliculi
“little canals” that connect lacunae and osteocytes to each other
osteoclast
cells that act to reabsorb or breakdown bone tissue
lamellae
concentric rings or tubes of bone matrix
chondrocyte
mature cartilage cell (usually trapped in lacunae); can divide
lacunae
a small cavity that often houses cartilage or bone cells
endosteum
a cellular membrane lining the spicule, trabeculae, canals, and medullary cavity of bone
chondroblast
immature cartilage cell that is responsible for matrix production; is close to O2 and nutrients
haversian (central) canal
canal lined with endosteum to supply blood vessels, lymphatics and nerve to bone; vertical canal that runs down the middle of an osteon
ossification
process of bone formation
mesenchymal cell
embryonic connective tissue cell that gives rise to all other connective tissue (common embryonic origin of all CT)
interstitial growth
cartilage growth due to mitosis of chondrocytes- may occur along epiphyseal plate of long bone to increase bone in length
appositional growth
growth of bone or cartilage due to the addition of bony matrix or cartilage to the outer surface (just under periosteum)
osteoblast
immature, matrix producing bone cell
periosteum
a thick, fibrous connective tissue layer surrounding the entire external surface of bone, with the exception of the articular surface
osteon
the functional and structural unit of compact bone- consist of tiny structural “pillars” made of concentric rings or tubes of bone
osteocyte
mature bone cell, usually trapped in lacunae, not active but provide structure
spicules of bone
tiny, needle-like bits of bone that connect to form trabeculae
hypertrophy
enlargement of cells
osteoid
organic components of the matrix (proteic fibers and ground substance) prior to mineralization
volkmann’s canal
contain blood vessels and nerves and run perpendicular to Haversian canals
what are the three types of connective tissue
connective tissue proper, supporting connective tissue, fluid connective tissue
functions of the skeleton
support of soft tissues of body
mineral reservoir- 98% of body’s calcium in bones
energy storage (yellow marrow)- fat stored in medullary cavity of long bones
blood cell production (red bone marrow)- in cavities of spongy bone
protection of vital organs
leverage and movement
connective tissue proper
-dense regular CT: aligned in a regular fashion; in ligaments, bone sheaths, tendons; have fibroblasts/cytes
-adipose: stored in bone; have adipocytes
supporting connective tissue
-cartilage: in joint discs, intervertebral discs, symphysis pubis; have chondroblasts/cytes
-osseous tissue: bone; have osteoblasts/cytes
fluid connective tissue
blood- formed in red bone marrow
cartilage characteristics
no blood vessels/nerves
consists primarily of water (60-80%)
surrounded by perichondrium
growth ends at 18-20 years
little healing in adulthood
collagen resists tension
poor at resisting “shearing forces” (tearing)
cartilage cells: chondroblasts and chondrocytes
perichondrium
-dense CT that surrounds cartilage
-like a girdle
-blood vessels here- help with growth/repair
-provides gas and nutrients to cartilage cells
hyaline cartilage
-most abundant
-has fibers (too small to see)
-located on end of bone, growth plate, costal cartilage
elastic cartilage
-many elastic fibers
-tolerates repeated bending, recoil
-located within ears/epiglottis (bendy areas)
fibrocartilage
-abundant collagen fibers
-retwisting and compression
-no perichondrium
-located in intervertebral disc, menisci
two types of osseous tissue
spongy bone and compact bone
every bone has:
blood vessels, nerves, and lymphatic vessels
spongy (cancellous) bone
-honeycomb-like network of bone
-form trabeculae (beams) to resist directional stresses; trabeculae surrounded by endosteum
-cavities filled with red bone marrow
-found in epiphysis and center of bone organ
-replaced every 4 years
compact bone
-beams of bone help to transmit weight within the bone
-allows compression down the medial diaphysis and tension along lateral diaphysis
-bone forms concentric rings of matrix (osteon)
-bone cells are trapped within cavities (lacunae)
-organized “nested rings” in periphery of bone
-replaced every 10 years
steps to change from spongy to compact bone
bone formation at the surface of the bone produces ridges that parallel a blood vessel
the ridges enlarge and create a deep pocket
the ridges meet and fuse, trapping the blood vessel inside the bone
organic compounds of the non-cellular matrix (osteoid)
-provide flexibility
-primarily: collagen fibers
-resists: twisting and tension
inorganic compounds of the non-cellular matrix (osteoid)
-provide durability and hardness
-calcium and phosphate
-98% of calcium held in bone
osteoclasts
-derived from WBCs
-breaks down old matrix (osteoid)
-releases calcium and phosphate
osteoprogenitor cells
-will form all new bone cells
-can divide
canaliculi transfer
-mineralized matrix so no diffusion through the matrix
-protoplasmic extension of adjacent cells can connect with canaliculi
-waste, nutrients, gas, etc. diffuse from cell to cell
intramembranous ossification
-bone develops between layers of fibrous membrane
-embryonic CT cells change into osteoblasts and form bone
what bones are formed by intramembranous ossification
flat bones (mainly in skull)- can be seen in fontanels (baby’s soft spots)
endochondral ossification
-cartilage model formed first
-bone replaces cartilage over time
-some cartilage remains at epiphyseal (growth) plate until growth ends
what bones are formed by endochondral ossification
mainly long bones of the body
bone grows in length until age ______
15-20
bone grows in width mainly until age ______
15-20 but will continue to form new bone for life
appositional growth
bone cell lays down new bone tissue along outside of bone (deep to periosteum)
in appositional growth, bone grows in _____
width
intersitial growth
-bone replaces cartilage, where cartilage cells have died
-occurs along epiphyseal (growth) plates
in interstitial growth, bone grows in _____
length
how much of your total body weight does muscle account for
40-50%
muscle characteristics
excitability
contractibility
extensibility
elasticity
muscle excitability
responds to external stimuli (hormones/nervous stimulus)
muscle contractibility
actively shortens along longitudinal axis
muscle extensibility
can stretch beyond original length, without tearing (contrast with brain, bone, spleen, or kidney)
elasticity
recoils to its original length
the muscle organ consists of
muscle fibers (cells) + connective tissue + nervous tissue + epithelial tissue
muscle function
change chemical energy into mechanical energywhat
mechanical energy in muscles is used to…
produce skeletal/skin movement
maintain posture/body position/joints
support soft tissue
regulate incoming and outgoing material- move material along tract
skmaintain body temperature (goosebumps, muscle contractions produce heat)
skeletal (somatic) muscle characteristics
striations
cylindrical fibers
multiple, peripheral nuclei
voluntary control
cannot divide
will fatigue over time
attached to skeleton and skin
every muscle organ has…
at least one artery, one vein, and one nerve
muscle cells/fibers
bundles of muscle cells = fascicles
connective tissue wraps the muscle organ into multiple tubes within a tube
arteries, veins, and nerves in muscle cells
-travel within CT to get to cells
-activate for contraction
-provide blood for cells
aponeuroses
a flattened, tendinous sheet derived from interwoven fibers of the endomysium, perimysium, and epimysium of skeletal muscle
endomysium
connective tissue covering surrounding a skeletal muscle cell (fiber)
epimysium
connective tissue (deep fascia) encircling many skeletal muscle fascicles
perimysium
connective tissue encircling a single skeletal muscle fascicle
fascicle
a bundle of many skeletal muscle cells (fibers)
myofilaments
contractile protein filaments consisting of mainly actin and myosin
thin myofilament
actin (contractile protein)
thick microfilament
myosin (contractile protein)
myofibril
bundles of myofilaments found in a single muscle cell
neuromuscular junction
junction of a motor neuron and a skeletal muscle fiber
sarcolemma
plasma membrane of a skeletal muscle cell (fiber)
sarcoplasmic reticulum
skeletal muscle cell endoplasmic reticulum; regulates calcium ion (Ca2+) storage and release to control muscle contraction
sliding filament theory
explains muscle contraction as the result of actin and myosin filaments sliding past each other within a sarcomere to shorten it and generate force
how is a tendon formed
blending and intertwining of the collagen fibers from the epimysium, perimysium, and endomysium