Biosythesis of RNA viruses

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25 Terms

1
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Examples of (+)ssRNA

Polio

Hep A

SARS

2
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(+)ssRNA can act as mRNA

True

3
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Where does the synthesis of new RNA viruses occur?

Cytoplasm

4
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What does (+)ssRNA lack?

Enzyme to make progeny

5
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What must (+)ssRNA be converted into in order to make RNA progeny?

(-)ssRNA

6
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What enzyme does (-)RNA have that is needed to make RNA progeny?

RNA dependent RNA polymerase

7
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Can (-)ssRNA act as mRNA?

NO

8
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(-)ssRNA undergoes ________ to make ________ to act as mRNA

transcription

(+)ssRNA

9
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At the same time that (-)ssRNA undergoes transcription to make (+)ssRNA, it undergoes ________ to make the (-)RNA progeny (copies)

transcription

10
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What genome carries RNA dependent RNA polymerase?

(-) RNA

11
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What is the disadvantage of (-)RNA? It can’t make the:

Protein coat (capsid)

12
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What must the (-)RNA make in order to produce a protein coat?

(+)RNA

13
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mRNA goes through the process of ________ in order to make the protein coat

translation

14
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What genome does a retrovirus have?

(+)ssRNA

15
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2 most known retrovirus

HIV

HTLV

16
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Receptors that must be present in order for the retrovirus to attach and enter the host cell

CD4

CCR5

17
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What type of spike protein do retroviruses have?

GP21

18
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Are retroviruses enveloped?

yes

19
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Three enzymes that the retrovirus carries

Reverse Transcriptase

Protease

Integrase

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What does the reverse transcriptase allow the retrovirus to produce?

DNA from RNA

21
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Retrovirus: After the DNA is transcribed from RNA, where does it go?

Nucleus (of host cell)

22
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With the help of the enzyme _______ the Viral DNA integrates into the host cell DNA (they become HIV positive)

integrase

23
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Retrovirus: After the viral DNA is integrated into the host DNA, it goes through the process of _______ to make mRNA

transcription

24
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Retrovirus: Through the process of _______, the mRNA makes the protein coat of the virus

translation

25
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Retrovirus: The enzyme _______ helps build proteins required for building the complete virion (with all the enzymes it needs)

protease