BTEC 3317 Quiz 1

What is the best definition of biotechnology?

The use of technology to improve organisms or their products for the benefit of man

The use of technology to improve animals

The use of technology to improve the environment

The use of technology to improve humans for the benefit of plants

The use of technology to improve organisms or their products for the benefit of man

3 multiple choice options

What was a major regulatory concern with FlavRSavR tomato?

The engineered enzyme is potentially allergenic

The engineered enzyme might cause indigestion

Agrobacterium tumefaciens, which could potentially cause disease in farm animals, was used to introduce the transgene

Agrobacterium tumefaciens which normally cause disease in plants was used to introduce the transgene

Agrobacterium tumefaciens which normally cause disease in plants was used to introduce the transgene

3 multiple choice options

Using a gene found in bacteria, many agricultural crops in the US have been genetically modified to be resistant to the herbicide, RoundUp. What is a major concern with plants genetically engineered to be RoundUp resistant?

The RoundUp resistance gene may increase disease incidence in plants

The RoundUp resistance gene can increase the plant susceptibility to insects

The RoundUp resistance gene can be passed on to difficult to control weeds.

The RoundUp resistance gene might kill pollinating bees

The RoundUp resistance gene can be passed on to difficult to control weeds.

3 multiple choice options

What was the main concern with the engineering of Bt toxin gene in crop plants?

The Bt toxin may cause neurological disorders in humans

The Bt toxin can cause indigestion in browsing deer

The Bt toxin may lead to herbicide resistant superweeds

The Bt toxin may kill beneficial insects

The Bt toxin may kill beneficial insects

3 multiple choice options

Vaccines against many diseases have been successfully produced in plants. Hepatitis B vaccine, to protect against hepatitis B virus, has been successfully produced in banana. What disorder does the Hepatitis virus cause?

Diarrhea and dehydration

Foot and mouth disease

Kidney damage

Liver damage

Liver damage

3 multiple choice options

The AquaAdvantage salmon was genetically engineered to be much faster growing than the native salmon counterpart. What is the main concern why FDA took 19 years to approve its commercialization?

An antibiotic resistance gene is present in the recombinant DNA that was used

It may lead to the extinction of native salmon species

It carries a virus that can kill the native salmon

The nutritional content has changed significantly compared to the native salmon

It may lead to the extinction of native salmon species

3 multiple choice options

What is one reason as to why earlier gene therapy clinical trials in humans had to be stopped by the Food and Drug Administration?

A patient acquired a viral infection from the viral vector used

Some patients refused to sign informed consent statements

A clinical trial participant died from hyperimmune response to the virus vector

Some patients acquired a functional immune system

A clinical trial participant died from hyperimmune response to the virus vector

3 multiple choice options

What is the main difference of modern from classical biotechnology?

Modern involves genetic improvement of living organisms while classical does not

Modern involves selective breeding while classical does not

Modern involves recombinant DNA technology while classical does not

Modern involves genetic manipulation while classical does not

Modern involves recombinant DNA technology while classical does not

3 multiple choice options

The Moderna and Pfizer vaccines for protection against coronavirus (SARS-COV2) consist of mRNA transcribed from recombinant DNA. Therefore, it would be classified under which stage of biotechnology?

Modern

Elevated

Ancient

Classical

Modern

3 multiple choice options

Which is not a major concern with xenotransplantation, or the use of animal organs in humans?

Possible carry over of viral pathogens from the donor animal into the human recipient

Some animals will reject the presence of human organs

The transplanted animal organ can get rejected by the human recipients immune system

Possible carry over of bacterial pathogens from the donor animal into the human recipient

Some animals will reject the presence of human organs

3 multiple choice options

What is a concern about genetically engineered plants?

The newly introduced gene may code for an allergenic protein

The engineered plant maybe more nutritious than the native plant

The engineered plant may have reduced levels of allergens

Beta carotene, which is a precursor for vitamin A, may be produced and cause blindness

The newly introduced gene may code for an allergenic protein

3 multiple choice options

What does not apply to vaccines?

Recombinant vaccines can be produced successfully in plants

Vaccines have contributed significantly to increasing the incidence of many infectious diseases

Some vaccines are classified as products of classical biotechnology while some are recombinantly produced

Inadequately inactivated microbes may cause disease when administered as vaccines

Vaccines have contributed significantly to increasing the incidence of many infectious diseases

3 multiple choice options

What is true of endotoxins?

A immunogenic substance produced by fungal pathogens of man

Not a main concern if the drug contaminant is a Gram positive bacteria

A drug contaminant that causes an out-of-control immune response in drugs that are formulated as syrups

An immunogenic substance found in the outer wall of most Gram positive bacteria

Not a main concern if the drug contaminant is a Gram positive bacteria

3 multiple choice options

The Genzyme plant in Massachusetts produces biotherapeutic enzyme replacement for people with Gaucher's disease. The plant was shut down by the FDA at one point causing a drug shortage concern for many patients. What was the reason for the shut down?

The cell cultures that churn out the therapeutic protein got contaminated with a virus

FDA found evidence of poor documentation or record keeping

FDA found unsanitary manufacturing conditions

Vials of the therapeutic protein were found contaminated with a simian virus

The cell cultures that churn out the therapeutic protein got contaminated with a virus

3 multiple choice options

The first genetically modified microorganism that was granted a patent was:

For producing a human protein used to control blood sugar levels

For producing a animal hormone which increases body mass and milk production

For use in cleaning up oil spills

For protecting plants against fungal pathogens

For use in cleaning up oil spills

3 multiple choice options