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Three aims of cancer treatment
Local: control primary tumor
Systemic: prevent or delay mets
Palliative care
Modalities used to treat primary tumors that are solid masses
Surgery
Radiation
± Additional therapies if surgery is dirty
Modalities used to treat primary tumors that result in systemic disease
Chemotherapeutics
Other targeted therapies
Modalities used to prevent or delay metastasis
Chemotherapeutics
Immunotherapy
Targeted therapies
Goals of palliation
Target impacts of cancer and target impacts of therapy
Direct impacts of cancer that we try to target with palliation
Pain
Paraneoplastic syndromes
Secondary infections
Impacts of cancer therapy that we try to target with palliation
Postop pain
GI signs
Inflammation
Easy and ideal type of sample to take in-clinic
FNA
Reasons you might not sample a cancer
Time, space AND