Sketchy Microbiology: Mucormycoses

Cain – Immunocompromised most effected

Jar of candy – Diabetes patients are susceptible

Baguette – Rhizopus is a bread mold

Coughing Mechanic — Transmitted via spore inhalation

Ketone auto parts — Diabetic Ketone Acidosis predisposes infection of this fungus

Tire iron — Hyphae are non-septate and have 90 degree angle branching

Red jumper cables — Fungus likes to proliferate into blood vessels

Oil pan w/ several holes - Fungus invades through cribriform plate in the skull → continues to cause necrosis of tissues and frontal cortex abscesses

Mechanic with oil dripping on face – will present as a black eschar and necrosis of nasal cavity and eyes, causing neuro deficits and death

What is the most important treatment?

Biopsy and Surgical debridement first, then antifungals

Frog Car – Treat with Amphotericin B