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From the point of fertilization to two weeks of gestation
Ovum
Develops into teeth, skin, fingernails, eye tissues.
Ectoderm
Develops into muscle, blood vessels, lymph, connective tissues, bone, cartilage
Mesoderm
Develops into respiratory epithelium, digestive system, liver, pancreas
Endoderm
From week 3-8 of gestation
Embryo
From week 9 through week 36 of gestation
Fetus
6 ridges of tissue, _________ _____ are present in the neck region.
Pharyngeal arches
U shaped bars of tissues containing a wire of tissue (cartilage, artery, nerve, muscle). The first is the ______ arch, second is the _____ arch, third is through arch VI.
Mandibular, hyoid arches
The external depression between arches is called..
Pharyngeal grooves
The internal surface of the depressions are called..
Pharyngeal pouches
Pharyngeal arches wrap around the hollow tube of the developing ________.
Digestive tract
The primitive digestive tract is divided into the ______, _____, and _____.
Foregut, midgut, and hindgut
________ is the primitive oral cavity, and ectodermal depression in front of the foregut.
Stomodeum
_____________________ is between the tongue and palatine tonsil area and when it breaks the connection between the OC and digestive tract is made
Buccal pharyngeal membrane
Facial development from an anterior view at 3 weeks shows...
Frontal prominence, stomodeum, mandible and maxilla process developing from the 1st pharyngeal arch.
Nasal pits form on the _______________ and they create medial and lateral halves.
Frontal prominence
The two medial halves grow together to form the ______
Lip
If there is an error when these two medial halves join it can cause a ___________.
Cleft lip
Created by the right and left maxillary processes and the medial nasal process
Development of the palate
The medial nasal process is an area of tissue that will be the area for the maxillary centrals and laterals as well as the incisive foramen is called the.....
Primary palate/premaxilla
The right and left maxillary processes grow inward towards each other at this point called...
Palatal shelves
Fluid filled sac that develops on midline of palate
Median palatine cyst
Fluid filled sac that develops where palatal shelves and primary palate together (btw max laterals and canine), typically is removed to prevent shifting of dentition
Globilomaxillary cyst
Occurs during weeks 7-11 of development, if it occurs early the entire palate can be open, the closer to week 11 it will only affect soft palate or uvula. More likely in males, hereditary and can be caused by use of alcohol, tobacco, and drugs
Cleft palate
Triangular median swelling, located on the midline on floor of primitive pharynx in embryo, does not form any portion of mature tongue
Tuberculum Impar
2 oval distal tongue buds on each side of the tuberculum impar, the two swellings over grow and encompass the disappearing tuberculum impar to form the anterior ⅔ of the tongue
Lateral tongue swelling
Posterior to lateral tongue swellings becomes the poster third of the tongue
Copula
Posterior to the copula and becomes the epiglottis
Epiglottic swelling
Fusion of lateral tongue swellings and copula, line forms inverted V shaped groove and becomes border between base of tongue and its body
Sulcus terminalis
Located at pit depression at the center of sulcus terminalis, starting point of the thyroid development
Foramen cecum
First sign of tooth development in embryo is during the _________.
6th week
Embryonic oral stratified squamous epithelium begins to thicken and grows _________.
Downwards
Begins at midline and develops posteriorly creating a "U" shaped thickening known as ____________.
Dental lamina
The enamel organ leads to the formation of _________.
Tooth enamel
The enamel consists of 4 layers?
Outer Enamel epithelium (OEE), Inner Enamel Epithelium (IEE), Stellate reticulum (SR), and Stratum intermedium (SI)
Three stages of enamel organ development
Bud stage, cap stage, and bell stage.
The Bud stage consists of three layers of cells
Superficial, basal, and dental lamina.
Buds grow and stretch out from dental lamina, bud begins to ______ and it enters the next stage
Concave
Cap stage now consists of what 3 components
OEE, IEE, and Stellate reticulum.
The outer most part of Cap, direct continuation of basal layer, cells are low columnar or cuboidal
Outer Enamel Epithelium (OEE)
Outlines the concaved portion of the Cap, identical to the cell of OEE but named due to location.
Inner enamel epithelium (IEE)
All the cells between the OEE and IEE
Stellate reticulum
A 4th component now exists alongside OEE,IEE, and SR
Bell stage
What stage does the outline of the tooth begin to form
Bell stage
Comprised of several layers of flattened squamous cells between IEE and SR
Stellate intermedium
During the bell stage, the IEE cells differentiate into ________ to form enamel.
Ameloblasts
Protects and guides the gingiva onto the tooth.
OEE
Differentiate into ameloblasts to create enamel
IEE
Protects IEE and nourishes SI
Stellate Reticulum
Produce protein and probably nourishes the IEE
Stellate Intermedium
Only found on primary teeth and is found on the lingual side of each tooth as an extension of dental lamina. Will go through each development stage and will become permanent incisors, canines and premolars
Successional lamina
Thickened oral epithelium on the buccal direction which will split and become the vestibule
Vestibular Lamina
Condensed cells under the bell which will differentiate into dentin and pulp
Dental papilla
Couple rows of flat cells at the bottom of the papilla which turn into cementum and periodontal ligament
Dental sac/follicle
-Differentiates into the dentin and pulp
And will determine shape of tooth crown
Dental papilla
(DP) Cells of the IEE elongate and change to __________ during bell stage
Ameloblast
Cells at the edge of the DP change to ___________ and move to the center of the DP and secrete dentin matrix
Odontoblasts
_____________ secrete enamel matrix thereby creating the DEJ and move towards the OEE cells
Ameloblast
Dentin and enamel both start to make _________ crystal and calcify
Hydroxyapatite
Dental papilla formation occurs in all teeth, primary or permanent
TRUE
If a primary tooth bud does not form can a primary or permanent tooth form?
No both will be congenitally missing
White hard 96 % inorganic, jewel like hydroxyapatite crystal is the molecule Ca (10)(PO4)6-(OH)2
Enamel composition
Outer organic component of enamel
Rod sheath
4 microns wide and extends to the surface
Enamel rod
Column of rods are __________ from DEJ to surface of tooth
Perpendicular
Rods are ______ shaped with the upper end being more wide the the bottom
Keyhole
Ameloblasts lay down the matrix and deposit millions of hydroxyapatite crystals within a few days, starts at the cusp tip and develops downwards toward CEJ
MIneralization stage
Crystals grow in size until tightly packed together
Maturation stage
Development of the rod which creates a microscopic brown line is called, these can be seen clinically on the facial surfaces of anterior teeth, Aka imbrication lines
Striae of retzius
As the ameloblasts move towards the OEE the SR and SI become.....
Squished
When the ameloblasts reach the OEE it signals them to_________
Cease enamel formation
Ameloblast lay down a protective layer over the enamel called....
Primary enamel cuticle or nasmyths membrane
The OEE and Ameloblasts are squeezed together and is termed
Reduced enamel epithelium (REE)
Reduced enamel epithelium fuses with the oral epithelium producing the _______________ which will hold the gingiva to the tooth
Secondary enamel cuticle or epithelium attachment
Cracks in enamel caused by trauma or developmental issues, Hairline cracks from dentin to enamel
Lamellae
Area of hypo calcified enamel at DEJ
Enamel tuft
An odontoplast process trapped between the enamel rods
Spindle
Normal Density but the enamel is thin, yellow or gray
Hypoplastic enamel
Not enough crystals, or loosely packed aka soft teeth
Hypocalcified enamel
Hard yellow 70 % inorganic, harder than bone but not as hard as enamel
Dentin
Extends from the DEJ to pulp, each houses an odontoblast process
Dentinal tubules
Surrounds the immediate tubules
Peritubular dentin
Everything else in dental composition
Intertubular dentin
For primary dentin, __________ begin to secrete dentin at the DEJ and migrate toward the pulp
Odontoblast
At the time of tooth eruption the dentin that exists is known as _____________.
Primary dentin
Layer of dentin closest to pulp
Secondary dentin
Is secondary dentin created by the same odontoblast as primary dentin
Yes
Forms in response to trauma and in that immediate area, can be occlusal, mechanical, or chemical trauma
Reparative dentin
Entrapped areas of poorly calcified spots
Interglobular dentin
Empty dentinal tubules that allow bacteria access to the pulp leads to rapid decay
Dead Tracts
When dentinal tubules are filled with dentin material due to trauma or decay
Sclerotic dentin
Develops from the dental papilla
pulp
Nerves of the pulp are mostly _____ and only transmit pain signals
sensory
_______ nerves can cause constriction of blood vessels within the pulp
autonomic
what begins at the cervical loop (where the OEE and IEE meet
Root formation
The two layers at the root OEE and IEE fuse and create the
Hertwig's epithelial root sheath (hers)
The heartwig's epithelial root sheath and the epithelial diaphragm determines ______
Shape and number or roots
The epithelial diaphragm grows apically and ______ with single rooted teeth.
Evenly
Two rooted teeth occur when the epithelium diaphragm grows inward at two opposite areas and meet in the ________.
Middle
3 rooted teeth occur when the epithelium diaphragm has 3 areas that grow ______.
Inward