Pathology of Lymphoma [080

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Last updated 5:42 PM on 12/1/23
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7 Terms

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Primary lymphoid follicle

Refers to an area in the lymph node where naive B cells are found.

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Secondary lymphoid follicle

Refers to an area in the lymph node where B-cell blasts are present.

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Immunophenotypic markers used in lymphoma pathology

CD3 is used to identify T-cells, CD20 is used to identify B-cells, and Ki67 is used as a proliferation index marker.

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Chronic non-specific lymphadenitis patterns

The three patterns are follicular hyperplasia, paracortical hyperplasia, and sinus histiocytes.

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Immunophenotyping to differentiate lymphoma or metastasis

CD45 is used, and if it is negative, it suggests metastasis. Leukocyte common antigen is also used.

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Tdt (terminal deoxynucleotide transferase)

An enzyme that is specifically expressed in pre-B and pre-T cells.

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Mycosis Fungoides

A type of peripheral T-cell lymphoma derived from mature post-thymic T-lymphocytes.