Pathology of Lymphoma [080

Questions

1) Whats the difference between Primary lymphoid follicle vs secondary

2) Which immunophenotypic markers are used in pathology of lymphoma?

3) Chronic non-specific lymphadenitis 3 patterns?

4)Immunophenotyping to differentiate if neoplastic lymph node is lymphoma or metastasis

5) What is Tdt (terminal deoxynucleotide transferase)?

6) What is Mycosis Fungoides derived from?

Answers

1) Primary: naive B cells 2ry: B - cell blasts

(2) CD3 -> T-cell, CD20 -> B-Cell, Ki67 -> Proliferation Index

3) Follicular hyperplasia, Paracortical hyperplasia, sinus histiocytes

4) CD45 -> if negative then metastasis , Leukocyte common antigen.

5) Enzyme specifically expressed in pre-B & pre-T cells

6) Peripheral T-cell lymphoma derived from mature post-thymic T-lymphocyte