Drugs without Positive Inotropic Effects

Unloader medications

1st line in the management of Chronic Heart Failure that are given in combination always

Diuretics

Class of drugs that reduce venous pressure and ventricular preload, it is classified under unloaders

ACE inhibitors in CHF

What class of drugs under unloaders that inhibit cardiac and vascular remodeling

• Dry irritating persistent cough

• Hyperkalemia

• Angioedema

• Fetal toxicity (Teratogenic)

Adverse effects of ACE inhibitors

ACE inhibitors

What class of drugs are teratogenic or may cause Renal Dysgenesis

Saralasin

ARBs med that does not end in -artans

ARBs

What drug class under Unlaoder medications that should be considered in patients intolerant of ACE inhibitors because of incessant cought

• Losartan

• Irbesartan

• Candesartan

ARBs drugs used for heart failure enumerate

• ACEi

• ARBs

• Used as cornerstone in treating heart failure

___ and ___ are considered base treatement component. which means?

• Isosorbide dinitrate and Hydralazine

• Amlodipine and Prazosin

• Nesiritide

• Bosentan and Tezosentan

Enumerate the Vasodilators in CHF

Patients that can not tolerate ACE inhibitors, especially for AFAM

ISDN + Hydralazine is used for patients who are specifically what

Nesiritide

Vasodilator in CHF that is considered as Brain Natriuretic Peptide

• Bosentan

• Tezosentan

Vasodilators in CHF that are considered as Endothelin Antagonist

Endothelin

A natural potent vasoconstrictor

• Bisoprolol

• Metoprolol succinate

• Carvedilol

• Nebivolol

Beta blockers are contraindicated to heart failure except these 4

Blocks B1 receptors in the kidney > Inhibits release of renin > inhibits RAAS

MOA of beta blockers in CHF

• Anti-arrythmic properties

• Antioxidant properties

Beta blockers are used for CHF and aside that it is also has what properties

• Compliance

• Diet

• Salt

• Fluid

• Alcohol

• Smoling

• Exercise

Non-pharmacologic therapy recommendation in treating heart failure