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Skin
What is the largest organ in the body?
Epidermis and dermis
The skin consists of what two principal layers?
Superficial layer
The epidermis is located on what layer of the skin?
Keratinized stratified squamous epithelium
The epidermis is made up of what type of cells?
Ectoderm
The epidermis is derived from which germ layer?
Avascular
Is the epidermis avascular or vascularized?
Deep layer
The dermis is located on what layer of the skin
Connective tissue
The dermis is made up of what type of tissue?
Mesoderm
The dermis is derived from which germ layer?
Highly vascularized
Is the dermis avascular or vascularized?
Hypodermis
What layer is deep to the skin (deep to the dermis layer of the skin)?
Loose connective tissue
The hypodermis is made up of what?
Vascularized
Is the hypodermis avascular or vascularized?
Epidermis
What layer of the skin is labeled 1?

Dermis
What layer of the skin is labeled 2?

Hypodermis
What layer is labeled 3?

Ectodermal cells
Initially, the embryo is covered by a single layer of what?
Periderm
At the beginning of 2nd month, epithelium divides, and a layer of flattened cells is laid down on a surface called?
Basal layer
At the end of the 4th month, the epidermis acquires its definitive 4 layer arrangement due to proliferated cells in what layer?
Periderm layer
Cells from what layer slough off in the amniotic fluid
Melanocytes
The epidermis is invaded by neural crest cells that will give rise to what cells in the Stratum Basale
Hair, nails, sebaceous gland, sweat gland
What are the skin appendages?
Ectoderm
What germ layer are skin appendages derived from?
Mesenchyme
What is the dermis derived from?
Somatic lateral plate mesoderm, paraxial mesoderm, neural crest
Teh dermis is derived from mesenchyme that has what 3 sources?
Paraxial mesoderm
What is labeled 1?

Splanchnic lateral plate mesoderm
What is labeled 2?

Somatic lateral plate mesoderm
What is labeled 3?

Somatic (parietal) and splanchnic (visceral)
What two layers does the lateral plate mesoderm split into?
Lines Intraembryonic cavity and surrounds the organs
What does the somatic and splanchnic layers of the lateral plate mesoderm surround?
Dermis in the limbs and body wall
What does the somatic lateral plate mesoderm form in the body?
Somites
What does the paraxial mesoderm organize into?
Sclerotome, myotome, dermatome
The paraxial mesoderm organizes into somites and the somites reorganize to give rise to what layers?
Dermatome
What becomes the dermis on the back?
Dermatome
What layer is labeled 1?

Myotome
What layer is labeled 2?

Sclerotome
What layer is labeled 3?

Paraxial mesoderm
What gives rise to the dermis on the back?
Neural crest
What gives rise to the dermis in the face and neck?