Essentials: Pharmacy Practice Quiz 1 LAB SHEET

What is the purpose of a basic metabolic panel (BMP)?

fluid status + acid/base status

What are included in BMPs?

sodium, potassium, chloride, bicarbonate (CO2), creatinine, blood urea nitrogen (BUN), glucose, calcium, estimated glomerular filtration rate (eGFR), anion gap

What is the purpose of sodium in a BMP?

hydration status + electrolytes

What is the purpose of potassium in a BMP?

regulation of nerve impulses, regulate muscle contractions, acid-base status, electrolyte

What is the purpose of chloride in a BMP?

hydration status, acid-base status, electrolyte

What is the purpose of bicarbonate (CO2) in a BMP?

acid-base status

What is the purpose of creatinine in a BMP?

kidney function test (often used to dose medications)

What is the purpose of blood urea nitrogen (BUN) in a BMP?

kidney function test

What is the purpose of glucose in a BMP?

assesses blood sugar level

What is the purpose of calcium in a BMP?

assess cellular functions, parathyroid gland, bones

What is the purpose of estimated glomerular filtration rate (eGFR) in a BMP?

calculation for assessing glomerular filtration rate of kidney (used in dosing medications + assessing kidney functions)

What is the purpose of anion gap in a BMP?

(calculation) electrolyte status + acid-base imbalance

What is included in liver function tests?

alkaline phosphatase (ALP), aspartate aminotransferase (ast), alanine aminotransferase (alt), bilirubin, total protein, albumin

What is the purpose of alkaline phosphatase (ALP) as a liver function test?

liver enzyme, (importance of significance is the differentiation of hepatobiliary disease + osteogenic bone disease

What is the purpose of aspartate aminotransferase (AST) as a liver function test?

liver enzyme, detection of hepatocellular damage to the liver

Why is an AST less specific than an ALT?

ALT has a wider distribution

What is the purpose of bilirubin an indicator as a liver function test?

breakdown product of hemoglobin in RBCs

What is the purpose of total protein an indicator as a liver function test?

albumin + globulin = total protein in serum (liver/kidney function)

What is the purpose of albumin as a liver function test?

synthesized in liver

What makes up a complete metabolic panel (CMP)?

BMP + LFT

What is the purpose of c-reactive protein (CRP) in a CMP?

acute phase reactant, non-specific indicator of inflammation

What is considered for a cardiac function?

creatine kinase (CK)

What does creatine kinase look for?

elevations in cardiac + skeletal muscle conditions

What is the purpose of CKMB in a CK?

an isoenzyme of CK, elevated levels of >=6% of total CK indicates acute myocardial infarction

What is the purpose of Troponin I (cTNI) in a CK?

specific marker for myocardial infarction, distinguishable from skeletal injury

What are considered pancreatic enzymes?

amylase + lipase (LPS)

What does amylase do as a pancreatic enzyme?

elevations indicate pancreatic disorders

What does lipase (LPS) do as a pancreatic enzyme?

(MORE SPECIFIC) elevations indicate pancreatic disorders

What are considered hormones?

human chorionic gonadotropin (hCG), thyroid stimulating hormone (TSH), triiodothyronine (T3) + thyroxine (T4)

What is human chorionic gonadotropin (hCG) + what does it test for?

hormone made by the placenta during pregnancy; elevations in urine/serum testing indicate pregnancy

What is thyroid stimulating hormone (TSH) + what does it test for?

thyroid function; when there is inadequate thyroid hormone in circulation, TSH secretion increases to stimulate increased thyroid hormone production

What is triiodothyronine (T3) + what does it test for?

thyroid function (most biologically active!); decreases/elevations indicate thyroid condition

What is thyroxine (T4) + what does it test for?

thyroid function; decreases/elevations indicate thyroid diseases/conditions