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Name the characteristics of ET (4) and the two main types
Cellularity, polarity, avascular yet innervated, and highly regenerative.
Epithelia and glands
What is the basement membrane?
Interface between ET and CT
What is the function of the basement membrane?
Attach epithelium to CT and serve as a barrier to the movement of large molecules between ET and CT
What are the two layers of the basement membrane
Basal lamina and reticular lamina
What is the basal lamina made of?
Collagen, and proteins and carbohydrates (proteoglycans)
What is the reticular lamina made of?
Reticular fibers, proteins and carbohydrates
What are junctions?
Points of contact between adjacent cell membranes
What are the 4 types of junctions?
Tight, adhering, desmosomes, and communicating (or gap)
Tell me about tight junctions
Fluid tight seal near apical surface
Tell me about adhering junctions
Forms completely around the cell that stabilizes the cell and maintains tissue integrity
Tell me about desomoes junctions
Like snap buttons between calls. Long thin strands that run from one plasma membrane to the other. Resistance to mechanical stress, stretch without tearing
Tell me about communicating (gap) junctions
Little tunnels that connect the intercellular space between two cells. Rapid diffusion and communication
What’s the biggest difference between covering and lining ET and Glandular ET
ET is vascular, the other is not
What are the functions of ET
Protection, transport, selective permeability, misc (page 6 notes for more details)
What are the number of layers called in ET?
Simple, stratified, pseudo-stratified
What are the cell shapes at the free surface of ET?
Squamous, cuboidal, columnar, transitional
What are possible modifications in ET?
Goblet cels, cilia, microvili, flagella
Cilia is ONLY on what type of cell shape?
Columnar
Microvilli are never on what cell shape?
Squamous
Transitional cells are always what shape and #of layers?
Cuboidal and stratified
Where would I find simple squamous ET in the body?
Blood vessels, lymph vessels, lung alveoli
Where would I find simple cuboidal ET in the body?
Ducts of small glands
Where would I find simple cuboidal with microvili?
Kidney tubule
Where would I find simple columnar ET in the body?
Ducts of small glands, stomach, intestines
Where would I find stratified squamous ET in the body?
Mouth, esophagus, vagina, anus
Where would I find transitional ET in the body?
Bladder, urethra, parts of the ureter
Where would I find pseudo-stratified ET in the body?
Nasal cavity, trachea, bronchi
What is the function of Glandular ET?
To secrete, tissue is modified and specialized for secretions
What are the 2 types of glandular ET cells?
Endocrine and exocrine
what does an endocrine cell do?
Release hormones into blood
What does an exocrine cell do and where would you find them?
Release substance via ducts to a free surface or lining. Mucus, sweat, oil, saliva, enzymes
What’s a goblet cell?
Single cell glands, secrete mucus to lubricant surfaces
What is mucus and where would you find it?
A lubricant to reduce wear and tear. Respiratory, GI, Reproductive tracts
Name the 3 classifications of exocrine glands
Merocrine, apocrine, Holocene
What’s a merocrine exocrine gland and where would you find it
Cells release product by exocytosis. Pancreas
What’s an apocrine exocrine glad and where would you find it?
A pics portion of cell pinched off with product
What’s a holocrine exocrine glad and where would you find it?
While cells are released with their contents. sebaceous glands