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Odontogenesis
The process of tooth development from initiation to maturation
Initiation, Proliferation, Morphogenesis, Cytodifferentiation, Apposition, and Maturation.
Tooth Development Stages
Enamel organ
A cap-like structure formed during the cap stage that contributes to enamel formation.
Dental papilla
Condensed ECTOMESENCHYME that forms during the cap stage, contributing to the formation of DENTIN and PULP.
Dental follicle
ECTOMESENCHYME surrounding the dental papilla that contributes to the formation of the periodontal ligament and cementum.
Cap Stage
phase in tooth development where the enamel organ, dental papilla, and dental follicle are formed.
Enamel Knot
A signaling center that regulates the growth and shape of the tooth during development.
Tooth agenesis
A condition where one or more teeth fail to develop due to genetic mutations.
BMP signaling
Bone Morphogenetic Protein signaling involved in regulating dental development, including the apoptosis of enamel knots.
Cervical loop
area where the inner and outer enamel epithelium meet, allowing for ongoing enamel production and root development
dental lamina breaks up, downward proliferation of cervical loop, differntial growth of IEE (inner enamel epithelium)
what occurs during bell stage
bell stage
stage of tooth development characterized by the differentiation of the inner enamel epithelium into ameloblasts and the outer enamel epithelium into odontoblasts.
Hyperdontia
A condition characterized by the presence of supernumerary teeth, mutations in signaling molecules (Wnt, FGF, Shh) BEFORE BUD stage
Hypodontia
A condition resulting in a reduced number of teeth due to developmental issues.
Oral epithelium
The epithelial layer involved in initiating the formation and development of teeth.
dentin
what does the ectomesynchyme form during odontogenesis
enamel
what does oral ectoderm for during odontogenesis
directs epithelium to form specific tooth
role of MESENCHYME in CAP and BELL stages
initiate tooth formation in mesenchyme
role of EPITHELIUM BEFORE bud stage