group 3 protozoans

is African sleeping sickness unicellular, acellular or multicellular

unicellular

is African sleeping sickness eukaryotic or prokaryotic

eukaryotic

what is the causative agent of African sleeping sickness

trypanosome brucei

where is african sleeping sickness generally found

sub-saharan africa

how is African sleeping sickness transmitted

Tsetse fly, vectorborne and zoonotic

signs and symptoms of african sleeping sickness

fever, headache, fatigue, swollen lymphs, aching, confusion, personality change, neurological problems/nervous system damage, sleep disturbances

how is african sleeping sickness diagnosed

microscopy of blood smear, lymph node aspirate or spinal fluid

classic signs/symptoms

sleeping disturbances, Winterbottom’s sign (enlarged lymph nodes

treatment

pentamidine, suramin, melarsoprol

how is african sleeping virus prevented

insect control, insect repellant, protective clothing

is chagas disease unicellular, multicellular or acellular

unicellular

is chagas disease eukaryotic or prokaryotic

eukaryotic

what is the causitive disease of chagas disease

trypanosoma cruzi

where is chagas disease found

Latin America, Mexico

how is chagas disease transmitted

triatomine bug vector, congenital, blood, zoonotic, contaminated food

signs and symptoms of chagas disease

acute phase: swollen skin/eyelids, fever, fatigue, loss of appetite, vomiting

chronic: cardiac disease, GI issues, neuro problems

how is chagas disease diagnosed

blood smear to show the bug, PCR to detect parasite DNA, elevated IgE and eosinophils

classic signs/symptoms of chagas

Romana’s sign (swelling of right eye), chronic cardiomyopathy, megacolon/megaesophagus

how is chagas disease treated

antiparasitics: benznidazole, nifurtimox

how is chagas disease prevented

insecticides, bed nets, blood screening

chagas virulence factors

obligate intracellular parasite