Adrenaline

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Last updated 3:02 PM on 6/7/26
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9 Terms

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Drug class

Sympathomimetic

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Mechanism of action

It stimulates the alpha and beta adrenergic receptors, causing blood vessels to constrict, the heart to beat faster and stronger, and the airway to dilate. Therefore, improving blood pressure increases cardiac output and opens the airways.

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Indications

Cardiac arrest, anaphylaxis, bronchospasm, bradycardia, croup, shock unresponsive to fluids

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Contraindications

nil

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Side effects

Hypertension, anxiety, tremors, palpations/tachyarrhythmias, dilated pupils

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presentation:

1 mg/1 mL ampoule

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Anaphylaxis

IM 500 mcg, repeated every 5 minutes, no maximum dose.

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NEB dose anaphylaxis administered for upper airway obstruction that is refractory anaphylaxis to 3 x IM adrenaline.

NEB 5 mg single dose

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Life-threatening bronchospasms or silent chest

500 mcg, repeat every 5 minutes no maximum dose