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Phineas Gage
25 year old construction foreman who got a tamping iron through his brain and out his skulls
he did recover but lost use of left eye
was changed after the accident
proved personality lives in the prefrontal cortex
Hemispatial Neglect
ignoring one side of the world exist
damage to the parietal lobe
can see the left side but chooses to ignore it
if damage is on right side of brain, you cannot see the left side of world
if damage is on left side of brain, you cannot see the right side of world
H.M
Henery Gustav Molaison, had surgery to relieve severe epilepsy at age 27 this removing hippocampus and other parts of his brain
anterograde amnesia but no longer had epilepsy attacks
capable of little if any new learning
could not make new memories
long term memory is sepearted from the hippocampus but you need the hippocampus to create new memories
frontal lobe
cognitive function
control of voluntary movements or activity
socially appropriate choices
parietal lobe
processes information from the senses
temperature, taste, touch, and vision
temporal lobe
processes memories
integrates memories with sensation of taste, sound, sight, and touch
occipital lobe
primarily for vision
central nervous system
the spinal cord and brain
is protected by bony structures(skull and vertebrae) and layers of soft protective tissue(meninges)
peripheral nervous system
all the nerves connecting the central nervous system to the rest of your body
the somatic and autonomic nervous system
somatic nervous system
controls voluntary muscle movement
go there, do this
autonomic nervous system
controls involuntary movement
heartbeat, pupil dilation, hormones
sympathetic nervous system
part of the autonomic nervous system that controls fight or flight responce
increase the function of systems that are needed to do the thing right now
decrease the function of the systems that can wait for better times
parasympathetic nervous system
part of the autonomic nervous system that conserves energy to be used later
increase function of the systems that can wait for better times
decrease function of the systems that are fight or flight
hypothalamus
links the nervous system and endorcrine system via the pituitary gland
key component of endocrine system
pituitary gland
a master gland that controls other glands throughout the body
key component of endocrine system
thyroid
regulates energy metabolism
key component of endocrine system
parathyroids
regulate calcium levels in bones and blood
key component of endocrine system
adrenals
involved in fight or flight response
key component of endocrine system
pancreas
regulates blood sugar levels
key component of endocrine system
the ovaries
secrete female sex hormone
key component of endocrine system
the testes
secrete male sex hormones
key component of endocrine system
endocrine operation when stressed
brain detects stressor then hypothalamus directs pituitary gland to release hormone to increase function of adrenal gland, adrenal gland releases cortisol, once brain detects elevated cortisol it tells hypothalamus that it has enough and system stops
how do brains vary across species
mostly the same layout across species; difference in size and wrinkles deals with amount and complexity of cortex
Forebrain/Neocortext
occipital lobe
temporal lobe
parietal lobe
frontal lobe
insular lobe
occipital lobe function
vison
temporal lobe function
hearing/object memory, knowing what things are, auditory processing
parietal lobe function
touch, spacial awareness, a map of the body’s skin surface
frontal lobe function
complex thought, planning, control of movement, map of the body’s muscles
insular lobe function
taste, awareness of internal organs
forebrain/subcortex
hippocampus
amygdala
basal ganglia
thalamus
hypothalamus
hippocampus function
memories of time and place, spacial navigation
amygdala function
emotional association
basal ganglia function
planning and executing movment
thalamus function
sensory pathways to and from the cortex
hypothalamus function
master controller of the brain and body, regulation of body hormones
midbrain
tegmentum
ventral tegmental area
substantia nigra
tegmentum function
eye and head orienting
ventral tegmental area function
reward pathway for the subcortical motor system
substantia nigra function
regulates basal ganglia subcortical motor system
hindbrain
pons
medulla oblongata
reticular formation
pons function
regulation of breathing, relays sensations to the cortex and subcortex
medulla oblongata function
vital survival functions including breathing and heart rate, critical reflexes such as coughing and swallowing
reticular formation function
arousal and attentiveness, sleep and wakefulness
aphasia
inability to speak properly
Wernickes aphasia symptoms
cannot understand words, but can speak
location: temporal lobe
areas of the brain that contributed to HM’s difficulties
temporal lobe
specifically the hippocampus
brain lobe that is disrupted in hemispatial neglect
parietal lobe damage
somatotopic map in the somatosensory corext
point-for-point correspondence of an area of the body to specific point on the central nervous system
proprioception
the sense of where and how our body is moving
how does the frontal lobe execute our intentions
motor cortex in the frontal lobe
somatosensory cortex in the parietal lobe
Brocas aphasia
inability to talk but still understanding words
location: frontal lobe
functions that prefrontal cortex regulates
motor cortex controls muscles
takes us towards something good and away from something bad
how is insula different from the other lobes, functions?
it is inside the brain
function: awareness of internal organs
subcortical regions different from the cortex
ancient and powerful structures supporting memory, emotions, and motivation
limbic system
limbic system
the part of the brain involved in our behavioural and emotional responses
hippocampus
amygdala
hypothalamus
place cells
neurons located within the hippocampus which are triggered in response to an animal/person entering specific places in its local environment
hippocampus is essential in forming what type of memory
helps humans process and retrive two types of memory
declarative memory: facts and events
spatial relationships
amygdala
it is a major processing center for emotions
The loss of the amygdala disrupts fear, but not other emotions
brain regions important for motivation and habit formation
motivation: nucleus accumbens
habit formation: caudate putamen
thalamus function
relays between cortical and subcortical regions, acts as a gatekeeper for messages passed between the spinal cord and the cerebral hemispheres
hypothalamus function
communicates information to and from endocrine or hormone systems, controls emotions also regulates body temperature and controls critical urges- such as eating or sleeping
dopamine producing brain areas
the midbrain region
substantia nigra
ventral tegmental
hypothalamus
what does dopamine do
teaches us about how to get more things we like, we feel pleasure, satisfaction, and motivation
hindbrain regions of brain
pons
medulla oblongata
cerebellum
synapse
connection between neurons
dendrites
projections from neurons, highly branched, equipped in additional protrusions called spines
receive signals form other neurons via synapse
cell body
middle part of a neuron
axon
single projection from the soma/cell body, little branching, protected by a myelin sheath, passes electrical signals down its length
sends/transmits signal to next neuron in a pathway via synapses at the axon terminal
axon terminal
side that axon is on in a neuron
myelin sheath
part of gila, prevents current dissipation through the axon membrane
how is the brain a social network
information is received in dendrite
summation of excitation is sufficient for action potential generation in the nucleus/axon
action potential and propagation through axon by myelin sheath
the information sent through the axon terminal
neuron organization
layered, some go deeper than others and others are more superficial
where are dopamine producing neurons located
located in the midbrain
cell body and dendrites located there
how do neuron send messages
through action potentials
action potentials
a temporary shift from negative to positive in the neurons membrane potential caused by ions suddenly flowing in and out of the neuron
when neurotransmitters leave the synapse
activate receptors
allows Na+ ions that change the charge of the neuron from negative to positive
agonist
mimics neurotransmitter, fits and can bind to receptor
antagonist
blocks other neurotransmitter so neurotransmitters cannot bind to receptor
endogenous opioids
opioid peptides or opiate peptides
peptides that bind to opioid receptors in the brain and mimic the effect of these peptides
glia
Support neurons, caretakers. Functions for structural support, bringing nutrients, removing wastes and speeding up electrical impulses. Wrap the myelin around the axon
sensory neuron
A sensory neuron in a spinal nerve carries the impulse into the dorsal root of the spinal nerve and into the spinal cord
motor neuron
Emerges out the ventral root of the spinal nerve and carries the impulse to an effector (quadriceps muscle)
interneuron
the sensory neuron synapses with an interneuron in the cord. The interneuron 'recognizes' the sensory input as part of a reflex and synapses with an appropriate motor neuron
three primary portions of the brain visible in early development in the womb
The forebrain
the midbrain
the hindbrain
size of cortex across species
The size of the frontal cortex and the number of convolutions in the cerebral cortex vary substantially from species to species
excitatory signal
depolarize the cell membrane, increasing the likelihood that the neuron will fire
inhibitory signal
electrical signals that prevent action
neural plasticity
brains ability to physiologically modify, regenerate and reinvent itself constantly over a lifetime
phantom limb syndrome
sensation of the presence of the amputated limb
its place in the brain is still reserved for some time, so the person's capacity to feel the finger's presence remains
Modal model of memory/three stage model
The traditional model of memory initially devised by Richard Atkinson and Richard Shiffrin. The modal model views memory as consisting of three stages or stores: sensory memory, short term memory (STM), and long-term memory (LTM).
Sensory memory
The memory stage that very briefly stores large amounts of fleeting sensory impressions. Sensory memory is comprised of iconic store (visual) and echoic (auditory)
function: to sustain sensations to identification
capacity: very large
duration: very short/ .5 sec-3sec
kinds of sensory memory
visual
auditory
touch
taste
smell
Sperling study measure duration and capacity of sensory memory
sperling flashed 12 letters to participants for 1/20 of a second and saw how many they could repeat back. he found that they could only recall a handful of letters. he concluded that our iconic memories capture the whole picture but it disapears before we can access it all
echoic memory
auditory sensory store
duration: 3 seconds
iconic memories
visual sensory store
duration: .5 seconds
short term memory(STM)
Memory store used for attending to information in the short term. Short term memory is limited in the length of time the memory can remain active- no longer than about 20 seconds. it is also limited that can be stored. No more than about four or five items or chunks of information. STM is one component of the modal model of memory
function: to do conscious work/to think
capacity: 7 plus or minus 2 chunks
duration: 10-15 seconds
chunking
giving meaning to a chunk of letters or numbers so they can be remembered easier
magic number of STM capacity
5-9
Peterson and Peterson study STM
Participants were asked to recall trigrams after intervals of 3, 6, 9, 12, 15 or 18 seconds. During the pause, they were asked to count backwards in 3's from a given number. This interference task was to prevent rehearsal
results: The longer the interval delay the less trigrams were recalled. Participants were able to recall 80% of trigrams after a 3 seconds delay. However, after 18 seconds less than 10% of trigrams were recalled correctly
attention
transfers information from sensory store to STM
if something get attention or focus it goes to STM