Untitled

What is this?

Intraosseous Abscess

What is this?

Syndactyly

What is this?

Craniostynostosis

What is this showing?

Fractures-found in osteogenesis imperfecta

What is this? What disease?

Blue sclera-found in osteogenesis imperfecta

What disease?

Achondroplasia

What does this histo slide show?

Osteopetrosis

What disease?

Osteopetrosis

What does this histo slide show?

* curvilinear shapes of the trabeculae mimic alphabet characters
* Found in Fibrous Dysplasia

What does this X-ray show?

Fibrous Dysplasia

What does this histo slide show?

Haphazard Spicules found in Fibrous Dysplasia

What are the brown spots? What disease?

Cafe au lait spots found in McCune-Albright Syndrome- associated with Polyostotic Fibrous Dysplasia

What disease?

Craniofacial involvement with polyostotic disease -Fibrous Dysplasia

What does this xray show?

Fibrous Dysplasia of the Proximal femur with Shepherd’s Crook Deformity

What does this xray show?

Polyostotic Fibrous Dysplasia

What does this histo slide show?

Osteitis Deformans - Jigsaw puzzle-like mosaic pattern appearance to lamellar bone

Sclerotic phase- prominent cement lines

What disease is this found in?

Left: normal Right: Paget’s Disease

Osteitis Deformans

What disease?

Cause of Headaches in Osteitis Deformans

What is this xray showing? What disease?

Bowing of weakened Pagetoid Bone

Sclerotic, irregular thickening of both cortical and cancellous bone - found in Osteitis Deformans

What is this xray showing?

Pagetic Tibia- Osteitis Deformans

What is this showing?

Myostitis Ossificans-bone formation in muscle

What is this?

Femoral Head with wedge shaped infarct- Osteonecrosis

What is this xray showing?

Legg-Calve-Perthes Disease

Idiopathic Avascular Necrosis of the hip

What does this histo slide show?

Synovial Chondromatosis

What is this showing?

Slipped Capital Femoral Epiphysis

What does this histo slide show?

Acute Osteomyelitis

What is this?

Acute Osteomyelitis

What is this?

Brodie Abscess found in Acute Osteomyelitis

What is this?

Intraosseous Abscess (Brodie Abscess) found in Acute Osteomyelitis

What is this xray showing?

Acute Osteomyelitis - Long bones showing radiolucencies

What is this? What is the green pigment called?

Pseudomonas Aeruginosa Osteomyelitis

Shows Green pigment - Pyocyanin

What is this showing? What disease is associated with this?

shows a draining sinus tract

Chronic Osteomyelitis

What is this xray showing and what disease is this associated with?

Osteomyelitis- Characteristic Xray: lytic focus of bone destruction surrounded by a zone of sclerosis

What is the arrow pointing at? What disease is this associated with?

Osteoporosis

Arrow = increased risk of fracture

What is this showing and what disease is this associated with?

Osteoporotic Vertebral Body-Osteoporosis

What does this histo slide show?

Osteoporotic Bone

What does this histo slide show?

Fracture

What is this showing?

Fracture

What does this histo slide show?

Rickets - Showing loss of normal cartilage palisades at costochondral junction

What does this histo slide show?

Normal bone matrix

What is this picture showing? What disease is this associated with?

Leg bowing due to poor mineralization - Rickets

What is this X-ray showing? What disease is it associated with?

Rickets- Epiphyses are open, mottled and overgrown

What is this X-ray showing? What disease is it associated with?

Adult with Osteomalacia and pseudofractures

What does this histo slide show?

Rickets- enlarged mass of uncalcified cartilage at costchondral junction

What is this X-ray showing? What disease is it associated with?

Rickets- Rachitic Rosary: beadlike prominences at junction of a rib and its cartilage

What disease does this child have?

Rickets- child has Rickets secondary to gluten sensitive enteropathy

Can also see Harris Sulcus groove (the arrow)

Frontal Bossing/squared head is prominent

What is this X-ray showing? What disease is it associated with?

Arrow shows Milkman Fracture

Aka: Looser Zone

What disease is this associated with?

Osteomalacia

What disease is this xray showing?

Osteomalacia

What does this histo slide show?

Von Kassa Stain (calcium) - Osteomalacia

surfaces of the bony trabeculae (*black*) are covered by a thicker than normal layer of osteoid (*pink/purple*) 

Exaggeration of Osteoid Seams

What is the arrow on left showing? on the right?

Arrow on left hand: Subperiosteal bone resorption

Arrow on right hand: Bulbous bulging from Brown Tumors

What does this histo slide show?

Hyperparathyroidism

What does this histo slide show?

Hyperparathyroidism

What is this gross path showing?

histologic changes of  hyperparathyroidism are known as osteitis fibrosa (refers to accelerated bone remodeling)

This can progress to *cystica*

What area in bone is this called?

Diaphysis

what area in the bone is this called?

Metaphysis

what area in the bone is this called?

Epiphysis

What does this histo slide show?

Osteoid Osteoma

What is this showing?

Osteoid Osteoma- Well-circumscribed lesion characterized by radiolucency with mineralized nidus (usually

What is this showing?

Osteoid Osteoma

What is this showing?

Osteoblastoma

What is this showing?

Osteoblastoma - Lucent, expansile mass involving spinous process at C5

What is this showing?

Osteosarcoma

What is this showing?

Osteosarcoma

What is this showing?

Osteosarcoma-

* Arrow: Radiographs show “sunburst” pattern, disruption of the cortex and lifting of periosteum forming “Codman triangle”

What is this showing?

Osteosarcoma

What is this showing?

Osteosarcoma

What is this showing?

Osteosarcoma

What is this showing?

Osteochondroma

What is this showing?

Osteochondroma

What is this showing?

Benign cartilage Cap- Osteochondroma

What is this showing?

Chondroma- Histologically comprised of well-circumscribed nodules of hyaline cartilage

What is this showing?

Chondroma

What is this showing?

Chondroma

What is A showing? B?

Maffucci Syndrome

A: multiple soft tissue masses and calcified thrombi

B: Contrast material filling cavernous hemangiomas of the soft tissues

What disease is this showing?

Chondrosarcoma

What disease is this showing?

Histology of grades 1, 2, 3 chondrosarcoma

What is this? What disease is this showing?

Cartilage growing within medullary cavity and                 through the cortex

Chondrosarcoma

What is this? What disease is this showing?

Malignant cells producing cartilage

Chondrosarcoma

What disease is this showing?

Chondrosarcoma - “cotton wool" appearance characteristic plain film radiograph finding

“popcorn” appearance on CT

What disease is this showing?

“cotton wool" appearance characteristic plain film radiograph finding - Chondrosarcoma

What disease is this showing?

Chondrosarcoma- Tumor arising from pelvic bone

What disease is this showing?

Chondrosarcoma- Tumor destroying bone

What disease is this showing?

Giant Cell Tumor of bone

Soap Bubble Appearance

What disease is this showing?

Giant Cell Tumor of Bone Histology

What disease is this showing?

Giant Cell Tumor of Bone- Gross Path Image

What disease is this showing?

Ewing Sarcoma

What disease is this showing?

Ewing Sarcoma Histology

What disease is this showing?

Ewing Sarcoma Histology

What disease is this showing?

Ewing Sarcoma

What disease is this showing?

Aneurysmal Bone Cyst

What disease is this showing?

Aneurysmal Bone Cyst

What disease is this showing?

Aneurysmal Bone Cyst

What disease is this showing?

Aneurysmal Bone Cyst

What disease is this showing?

Aneurysmal Bone Cyst

What disease is this showing?

Chordoma

What disease is this showing?

Chordoma

What disease is this showing?

Metastatic Tumor

What disease is this showing?

Metastatic Prostate Carcinoma

What disease is this showing?

Metastatic Breast Carcinoma to vertebral body