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Anatomy
the study of the structure of the body parts individually and their relations to each other
Gross anatomy
structures that can be seen with the naked eye
Microscopic Anatomy
structures too small to be seen with the naked eye
Physiology
the study of how the body and its parts work or function
To understand physiology, you must understand the basics of _____ _________ and _________
cell structure and chemistry
All organisms are built with the same fundamental _______.
molecules
What are the levels of structure?
chemical, cellular, tissue, organ, organ system, organismal
Chemical Level
atoms make molecules
Cellular Level
molecules make cells
Organ Level
tissues make up organs
Organ System Level
organs work together
Organismal Level
Organ systems make up the human organism
______ and _______ _______ work together to help the body survive.
cells and organ systems
tissues and cell (can/ can't) function in ____________.
isolation
Homeostasis
the ability to maintain a steady internal state despite external change
Dynamic Steady State
things are constantly changing and must be actively compensated for to maintain homeostasis
What process involves the inability to maintain homeostais?
disease process
Homeostasis requires the detection and to response to _________ changes
physiological
Homeostatic control is mediated by a ______ _______.
control loop
Control loop
1) Stimulus
2) Receptor
3) Receptor sends input to the control center
4) Control Center
5) Control center sends output
6) Effector
Stimulus
changes in a variable that is regulated
receptor
structure that detects a stimulus
Control center
integrates input and initiates changes through the effector (usually endocrine gland or brain)
effector
the structure that brings about the change to alter the stimulus
_______ _______ impact the control loops
feedback mechanisms
afferent pathways
stimulus to control center
efferent pathways
control center to effector
Negative feedback loop
inhibits stimulus (turns response OFF)
Positive feedback loop
enhances stimulus (PROLONGS response)
Negative loops keep internal or external environments stable and are sometimes or always occurring?
internal, always
Which type of feedback loop requires an off switch?
positive
atoms
smallest building block of life
elements
smallest unit with individual properties on composition
macromolecules
Bigger molecules: DNA, RNA, Proteins, Carbohydrates, & Lipids
Elements
1. Oxygen
2. Carbon
3. Hydrogen
4. Nitrogen
5. Potassium
6. Sodium
7. Chlorine
8. Calcium
9. Phosphrous
10. iodine
11. Vandium
What element is associated with respiration and ATP generation?
oxygen
Which elements are the building blocks of macromolecules (DNA & Proteins)?
Carbon, Hydrogen, & Nitrogen
Which elements are present in electrically excitable cells?
Potassium, Sodium, & Chlorine
Which elements are necessary for bone formation and homeostasis?
Calcium & Phosphorus
Which elements are involved in thyroid hormone synthesis?
Iodine & Vandium
Everything in the body is made of a huge network of atoms held together by _______ ________.
chemical bonds
Inorganic molecule
NO carbon
Organic molecule
many carbons
Elements bond with other elements to form ______________ and ____________.
molecules & macromolecules
Types of bonding
- ionic
- covalent
- hydrogen
Ionic bonding
oppositely charged molecules & form weak lattice structures
Covalent bonding
highly stable bonds & share electrons (strongest bond)
Hydrogen
fairly weak and between 2 polar molecules
Water is the most important _______ molecule of the body
inorganic
Polarity
the distribution of charge across a molecules
Polar molecules have _______ _______ _______
unequal charge distribution
What does unequal charge distribution allow for in polar molecules?
Cohesion
Cohesion
the association of water molecules
Electro-attractive forces
2 molecules pulled together because they are oppositely charged
What do electro-attractive forces allow for?
hydrogen bond formation
A _________ is a mixture that has the same composition throughout
solution
Solvent
majority of the solution (everything suspended) in)
Solute
what's dissolved in solvent
Solvency
the ability of water to dissolve & separate ions
Ions
atoms with different charges
Because water is polar, it can dissolve many polar/nonpolar molecules?
polar
Hydration Spheres
The partially negative charge orients towards the positively charged ion (and visa versa)
Hydrolysis
water can break down bonds holding molecules together
Dehydration Synthesis
water can be the product of 2 molecules attaching
What has a high ______ capacity
heat
High heat capacity
Hydrogen bonding allows water to resist changes in temperature
Is water acidic, neutral, or basics on the pH scale?
neutral (7)
Acids
Molecules that release hydrogen when dissolved in water (more H+)
Bases
molecules that adsorb hydrogen from solutions (less H+)
Most minerals are obtained through ______, and most gases are obtained through ____________.
diet, respirtation
Roles of minerals in the body
1) calcification of bones
2) action potential of muscles and nerves
Which 3 minerals build bones?
Calcium, Phosphorus, and Potassium
All molecules of life are assembled from __________ components
organic
Carbon can bond with ____ atoms, and create ________, _______, or ______ bonds
4, single, double, or triple
If there is at least 1 double or triple bond, the the carbon is _____________ meaning it lost a H+ from the bond.
unstaurated
The chemical properties of a carbon link are determined by what two things?
1) Length of chain
2) functional groups associated with the chain
Molecules of life
carbohydrates, lipids, proteins, nucleic acids
What determines the properties of organic molecules?
functional groups
Macromolecules
large organic molecules that contain thousands of linked atoms
Polymers
macromolecules consisting of repeating monomers
Monosaccharides
simple sugars that are one ring composed of 5 or 6 carbon atoms
How and why are simple sugars made?
they are made by the breaking down of more complex sugars to provide quick sources of energy for the cell
Dissacharides
"Double sugars" are formed when 2 monosaccharides bond through dehydration synthesis
Polysaccharides
complex sugars composed of many linked monosaccahrides
A linear plant-based polysaccharide consisting of straight or slightly branched lines of glucose monomers
starch
A branched animal polysaccharide consisting of highly branched lines of glucose monomers
glycogen
What polysaccharide is stored in the liver and muscle cells and is broken down into glucose when blood sugar drops?
glycogen
Lipids are _______, _______ molecules thar are composed mostly of Carbon and Hydrogen.
insoluble, hydrophobic
What are the three Lipid subclasses?
triglycerides, phospholipids, and steroids
What do Lipids do?
energy source, insulation, cell membranes, structural support, and cellular communciation
Triglycerides have ___ fatty tails and are used to store ______.
3, energy
What is the term for the dehydration synthesis of lipids?
lipogenesis
Fatty acid tails saturation helps determine the ________ of a substance.
fluidity
What are the two types of neutral fats?
saturated and unsaturated
Saturated fats are ______ packed and _______ at room temperature, while unsaturated fats are _______ packed and ______ at room temperature.
tightly, solid; loosely, liquid
To make energy, fatty acids chains are connected to _____ carbons.
acetyl coA
What does it mean for a phospholipid to be amphipathic?
Some portions are hydrophobic while other parts are hydrophilic.
Phosoplipids
modified amphipathic triglycerides that form cell membranes and barriers that contain 2 fatty acid tails
Steriods are unique _____ composed of 4 ________ _______
lipids, hydrocarbon rings
Steroids are determined by the different ______ ______ attached to the ____ _______ __________
functional groups; 4 hydrocarbon rings