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What is the goal of transplant medicine?
The goal is to minimize alloreactions to prevent solid organ rejection and graft-versus-host disease.
What is HLA typing?
HLA typing uses genetic tests to determine similarities between the polymorphic HLA molecules of the donor and recipient.
How do fewer HLA mismatches affect transplant success?
Fewer HLA mismatches increase the chance that a transplant will be accepted by the recipient’s immune system.
What is crossmatching?
is performed to test for the presence of preexisting HLA immunoglobulins in the recipient.