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Ebola/ marbug Virus
Signs and symptoms- Capillary fragility is extreme and patients can bleed from their orifices and mucous membranes.
infective source- direct contact, body fluids, bats?
diagnosis- PCR viral culture (conducted at CDC)
treatment- New drugs developed for ongoing outbreaks in Africa
Prevention- New Ebola vaccine tested and approved in 2016
Hantavirus
Infective source- vehicle airborne virus emitted from rodents
diagnosis- serology (IgM), PCR identification of antigen in tissue
treatment- supportive
prevention- avoid mouse habitats and droppings
Hantavirus
Also referred to as Pulmonary Syndrome
Hantavirus
signs and symptoms- Prodromal phase includes- fever, chills, muscle aches, headache, nausea, vomitting, diarrhea, acute lung symptoms- severe breathing difficulties
SARS Coronavirus
A Virus
infective source- droplet contact, airborne
diagnosis- RT-PCR, Ab and Ag tests
treatment- antivirals such as Paxlovid
prevention- vaccine mitigation efforts
SARS Coronavirus
signs and symptoms- acute respiratory symptoms vomiting and diarrhea affects cells of the nervous system loss of taste and smell. Infections may be mid and asymptomatic.
Coccidioides immitis
infective source- vehicle ( air dust and soil)
Diagnosis- Identification of spherules, cultivation on sabourauds agar
Treatment- fluconazole or amphotericin B
prevention- Avoiding airborne endospore
Coccidioides immitis
signs and symptoms- fever, cough, chest pain, cold, rashes, night sweats, joint aches, etc. If condition worsens can cause weight loss, nodules in lungs and ulcers and skin lesions.
Coccidioides immitis
Also reffered to as Valley Fever
RSV Respiratory syncytial Virus
A Virus
shape syncytia formation
infective source- droplet and indirect contact
diagnosis- RT-PCR
treatment- Ribavirin plus passive antibody in severe cases
prevention- Passive antibody (humanized monoclonal) in high-risk children
RSV Respiratory syncytial Virus
signs and symptoms- Fever for 3 days, rhinitis, pharyngitis, and otitis, dyspnea and abnormal breathing (rales). Condition is called “croup” and bronchiotis
Erythema infectiosum
A Virus
Infective source- droplet contact, direct contact
Diagnosis- Diagnosed clinically
Treatment- none
Prevention- none
Erythema infectiosum
signs and symptoms- A sudden bright red rash across the cheeks that looks as if the child has been slapped. May also be called slap cheek syndrome
Erythema infectiosum
Also known as the fifth disease
Histoplasma Capsulatum
A Fungi
infective source- vehicle inhalation of fungal spores in contaminated soil
Diagnosis- rapid antigen tests; microscopy
Treatment- Itraconazole
Prevention- Avoid soil contaminated with bird and bat droppings
Histoplasma Capsulatum
signs and symptoms- Most people will have no symptoms. A person with a weak immune system may experience fever,; headache, dry cough/ blood, chills, muscle aches, chest discomfort, joint pain
Taxoplasma gondii
A Parasite
infective source- vehicle (meat) or fecal- oral
Diagnosis- serological detection of IgM, culture, histology
treatment- Pyrimethamine or Leucovorin and sulfadiazine
Prevention- Personal hygiene, food hygiene
Taxoplasma gondii
Signs and symptoms- Mild symptoms such as sore throat, lymph node enlargement, low-grade fever. Extensive brain lesions and fatal disruptions of heart and lungs. Pregnant women may also be infected.
Mycoplasma Pneumophila
A Bacteria
gram + shape adhesions
Diagnosis- Rule out other etiologic agents; serology; PCR
infective source- Droplet contact
Treatment- Erythromycin
Prevention- No vaccine, no permant immunity
Mycoplasma Pneumophila
Signs and symptoms- Dry cough, fatigue, headache, fever, sore throat. Other symptoms may include bronchitis, mild shortness of breath, and infections of the middle ear.