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100
Most insulin products contain ________ units/mL of insulin.
10
Insulin comes in vials, usually containing ________ mL.
3; 1.5
All insulin pens contain ________ mL of insulin, except for Toujeo which is also available in a(n) ________ mL size.
reduces injection volume
Why is concentrated insulin useful?
regular insulin U-500
The concentrated insulin that comes in both a pen and a vial is ________, which has higher risk.
Humalog KwikPen, Lyumjev KwikPen
What are 2 rapid-acting concentrated insulins?
200
Rapid-acting concentrated insulin is available as ________ units/mL.
Humulin R U-500
What is a brand name for short-acting concentrated insulin?
500
Short-acting concentrated insulin is available as ________ units/mL.
Toujeo SoloStar, Tresiba FlexTouch
What are 2 brand names for long-acting concentrated insulin?
200
Tresiba FlexTouch is a long-acting concentrated insulin available as ________ units/mL.
300
Toujeo SoloStar is a long-acting concentrated insulin available as ________ units/mL.
true
True or False: Tresiba FlexTouch U-100 and U-200 pens would both be dialed to 80 units to deliver an 80 unit dose.
>200
Humulin R U-500 insulin is useful for patients taking ________ units/day.
4 pens
35 x 30 = 1050
1050 / 300 = 3.5
If a patient is taking 35 units of Lantus daily, how many Lantus SoloStar pens would be dispensed to provide a 30-day supply?
refrigerator
How are unused insulin vials, pens, and cartridges stored?
manufacturer's expiration date
What is the expiration date of insulin that's been stored in the refrigerator?
room temperature
How are opened/used insulin vials, pens, and cartridges stored?
28 days
Most insulin is stable at room temperature for ________.
10 days
What is the room temperature stability of Humalog Mix 50/50 and 75/25 pens?
10 days
What is the room temperature stability of Humulin 70/30 pens?
14 days
What is the room temperature stability of Humulin N pens?
14 days
What is the room temperature stability of Novolog Mix 70/30 pens?
28 days
What is the room temperature stability of Apidra, Humalog, Novolog, Admelog, Lyumjev, and Fiasp vials?
28 days
What is the room temperature stability of Apidra, Humalog, Novolog, Admelog, Lyumjev, and Fiasp pens?
28 days
What is the room temperature stability of Humalog Mix 75/25 vials?
28 days
What is the room temperature stability of Novolog Mix 70/30 vials?
28 days
What is the room temperature stability of Novolin R U-100, N, and 70/30 pens?
28 days
What is the room temperature stability of Humulin R U-500 pens?
28 days
What is the room temperature stability of Lantus, Basaglar, and Semglee vials?
28 days
What is the room temperature stability of Lantus, Basaglar, and Semglee pens?
31 days
What is the room temperature stability of Humulin R U-100, N, and 70/30 vials?
40 days
What is the room temperature stability of Humulin R U-500 vials?
42 days
What is the room temperature stability of Novolin R U-100, N, and 70/30 vials?
42 days
What is the room temperature stability of Levemir vials?
42 days
What is the room temperature stability of Levemir pens?
56 days
What is the room temperature stability of Tresiba pens?
56 days
What is the room temperature stability of Toujeo pens?
<30
0.3 mL insulin syringes are for volumes that are ________ units.
30-50
0.5 mL insulin syringes are for volumes that are ________ units.
51-100
1 mL insulin syringes are for volumes that are ________.
green
What color are U-500 insulin vial caps and syringe needle covers?
orange
What color are U-100 insulin syringe needle covers?
thinner
The higher the pen needle gauge, the (thicker/thinner) the needle.
shorter; higher
(Longer/Shorter) and (higher/lower)-gauge pen needles cause less pain.
4; 5
The shortest pen needles are ________ mm and ________ mm in length and are preferred for most insulin pens.
false
True or False: 4 mm and 5 mm pen needles require the skin to be pinched during administration.
true
True or False: 8 mm pen needles are long enough for most patients and require the skin to be pinched up before injecting.
false
True or False: 12.7 mm (1/2) inch pen needles do not require the skin to be pinched up before injecting.
BD
What is a common brand for insulin pen needles and syringes?
true
True or False: Insulin pens containing NPH or protamine should be inverted to resuspend the suspension.
2
Prior to each insulin pen needle injection, prime the needle by turning the knob to ________ unit(s), face the needle away from you, and press the injection button.
clear; cloudy
If mixing NPH and regular or rapid-acting insulin in the same syringe, the (clear/cloudy) insulin should be drawn into the syringe before the (clear/cloudy) insulin.
abdomen
At what injection site is insulin best absorbed?
2-inch
With insulin needles >5 mm, gently pinch a(n) ________ portion of skin between your thumb and first finger.
90
Insulin pens are injected into the skin at a(n) ________º angle.
90; 45
Insulin syringes are injected at a(n) ________º angle for most or ________º angle if the patient is thin.
5-10 seconds
When injecting insulin, count ________ before removing the needle.
false (should do this to prevent skin damage)
True or False: Insulin injection sites do not have to be rotated.
sharps disposal container
Where should used insulin needles, syringes, single-dose pens, and lancets be disposed of?
blood glucose monitoring
refers to patients tracking their blood glucose using a glucose meter or a continuous glucose monitor
interstitial fluid
Continuous glucose monitor probes provide measurements of the glucose level in the ________.
true
True or False: Glucose meter test strips should be kept in the original container with the cap closed.
side of fingertip (less painful)
Where should you prick the finger with a lancet when checking your blood glucose?
forearm, palm, thigh
What are 3 alternative glucose testing sites approved by some glucose meters?
steady
Alternative testing sites are only useful when the blood glucose is (fluctuating/steady).
after eating, after exercise, suspected hypoglycemia
What are 3 times when alternative blood glucose testing sites should not be used?
<70
Hypoglycemia is defined as a blood glucose of ________ mg/dL.
fall
What is a severe consequence of low blood glucose?
cognitive impairment
Each hypoglycemia episode contributes to irreversible ________.
anxiety, confusion, hunger, irritability, palpitations, shakiness, sweating, tremors
What are 8 symptoms of hypoglycemia?
coma, death, seizures
What are 3 things severe hypoglycemia can cause?
glucose
What is preferred to treat hypoglycemia?
take 15 g glucose; recheck BG after 15 minutes; if hypoglycemia continues take 15 more g glucose and recheck after 15 minutes; once BG is normal eat a small meal or snack
What is the "rule of 15"?
rule of 15
What method is used to treat hypoglycemia?
dextrose; glucagon
When oral treatment is not possible for hypoglycemia, treat with ________ if IV access is available or with ________ if IV access isn't available.
1 mg SC injection, nasal spray
Caregivers of someone at high risk for hypoglycemia should know how to use what 2 glucagon preparations?
lateral recumbent
If using glucagon to treat hypoglycemia in an unconscious patient, place the patient in a(n) ________ position to protect the airway and prevent choking when consciousness returns.
insulin
What is the primary cause of drug-induced hypoglycemia?
meglitinides, sulfonylureas
What 2 drug classes are high-risk for causing hypoglycemia?
glimepiride, glyburide
What 2 sulfonylureas are not recommended in the elderly due to hypoglycemia risk?
DPP-4 inhibitors, GLP-1 agonists, SGLT2 inhibitors, thiazolidinediones
What 4 diabetes drug classes have a low risk for hypoglycemia when used alone?
1 serving glucose gel, 1 tbsp sugar/honey/corn syrup, 3-4 glucose tablets, 4 oz juice, 4 oz regular soda, 8 oz milk
What are 6 examples of 15 g of simple carbs that can be used to raise blood sugar when treating hypoglycemia?
alcohol
________, especially if taken on an empty stomach, can cause hypoglycemia when used with insulin or sulfonylureas.
beta-blockers; non-selective
________, especially if (non-selective/selective), can cause hypoglycemia and mask adrenergic symptoms of hypoglycemia.
hunger, sweating
What 2 hypoglycemia symptoms are not masked by beta-blockers?
beta-blockers, quinolones
What 2 drug classes can cause either hypoglycemia or hyperglycemia?
tramadol
What non-diabetes drug can cause hypoglycemia?
antipsychotics, cough syrup, cyclosporine, loop diuretics, niacin, protease inhibitors, statins, steroids, tacrolimus, thiazide diuretics
What are 10 drugs/classes that can cause hyperglycemia?
olanzapine, quetiapine
What are 2 examples of antipsychotics that can cause hyperglycemia?
140-180
The target blood glucose range for most non-critical and critical care patients in the hospital is between ________ mg/dL.
false (this is discouraged)
True or False: The use of sliding scale insulin alone to control blood glucose in the hospital setting is encouraged.
insulin
What is used to treat most hospitalized patients with diabetes?
basal/bolus/correction dose regimen
What regimen is preferred to treat patients with diabetes in the hospital when oral intake is adequate?
insulin sensitivity factor; correction factor
A hospitalized patient's correction dose scale is designed based on the patient's ________, which is the same as the ________.
rapid-acting, regular
Inpatient insulin sliding scales and correction doses use what 2 types of insulin?
rapid-acting
What type of insulin is preferred for inpatient insulin sliding scales and correction doses, rapid-acting or regular?
diabetic ketoacidosis
life-threatening crisis with high blood glucose, ketoacidosis, and ketonuria
1
Diabetic ketoacidosis is most common in type (1/2) diabetes.
diabetic ketoacidosis
________ is commonly the initial presentation in type 1 diabetes or caused by insulin non-adherence or subtherapeutic insulin dosing.