somatic nervous system

What is somatic nervous system?

it’s voluntary, impulses originate in CNS.

ACH acts on nicotinic 2/ Nm receptors

Skeletal muscle relaxants?

Inhibit skeletal muscle contraction and can be central or peripheral acting

Peripheral skeletal muscle relaxants?

Are depolarizing agents, no antidote

Peripheral skeletal muscle relaxants?

Occupies the nicotinic 2/ Nm receptor sites, ACH cannot bind, no contraction occurs. Can cause fasciculations (pain,hypotension,arrhythmias,jaw rigidity)

peripheral skeletal muscle relaxants?

Blocks Ca++, does not effect the nicotinic 2/Nm receptor or spinal cord conduction. Can be toxic to liver

Centrally acting skeletal muscle relaxants?

Decreases number of impulses, block conduction writhing the spinal cord. Can cause blurred vision, fatigue patients need to avoid alcohol and operating a vehicle.

succinylcholine (no antidote)

Is a skeletal muscle relaxant, depolarizing agents

Rocuronium bromide

Is a skeletal muscle relaxant, Non- depolarizing agent

Dantrolene (dantrium)

Skeletal muscle relaxant, Direct Acting

Cyclobenzaprine

skeletal muscle relaxant, centrally acting

Carisoprodol (soma)

Skeletal muscle relaxant, centrally acting

Methocarbamol

Skeletal muscle relaxant, centrally acting

Orphenadrine citrate

Skeletal muscle relaxant, centrally acting

Chlorzoxazone

Skeletal muscle relaxant, centrally acting

Metaxalone

Skeletal muscle relaxant, centrally acting