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Cytokines
Chemical messengers produced by stimulated cells that affects the function or activity of other cells
Autocrine
Cytokine acts on the cell that secreted it
Paracrine
Cytokine acts on nearby cells
Endocrine
Cytokine travels through blood vessels to distant cells
Pleiotropy
Many diff. actions of a single cytokine
Redundancy
Different cytokines activate some of the pathways and genes
Synergistic
Effects complement and enhance each other
Antagonism
One cytokine may counteract the action of another cytokine
Cascade induction
Cytokine secreted by a specific type of cell can activate target cells to produce additional cytokines