Apomorphine for ED Real Does It Improve Sexual Performance?

Apomorphine

A dopamine receptor agonist used to treat erectile dysfunction by stimulating dopamine pathways in the brain.

Mechanism of Action of Apomorphine

Works centrally in the brain to enhance sexual motivation and facilitate erections, differentiating it from PDE5 inhibitors that focus on increasing blood flow.

Sublingual Tablet

A form of medication placed under the tongue for rapid absorption into the bloodstream, used for adminstering apomorphine.

Psychogenic ED

Erectile dysfunction caused by psychological factors such as anxiety or depression, where apomorphine may be particularly effective.

Nitric Oxide (NO)

A compound that relaxes penile blood vessels, indirectly boosted by apomorphine to improve erectile quality.

Onset Time for Apomorphine

Effects of apomorphine begin within 10-20 minutes after administration.

Efficacy

Apomorphine is most effective in cases of psychogenic erectile dysfunction compared to organic erectile dysfunction.

Limitations of Apomorphine

Apomorphine has moderate efficacy, common side effects like nausea and dizziness, and is not FDA-approved in the U.S.

Who Should Consider Apomorphine?

Ideal for men with psychogenic ED unresponsive to PDE5 inhibitors, seeking fast-acting treatment without cardiovascular risks.

Contraindications for Apomorphine

Includes severe liver/kidney impairment, history of fainting or hypotension, and concurrent use of other dopamine agonists.