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Science
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Inflammation
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Pathology
University/Undergrad
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21 Terms
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1
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Reversible
________: mild or moderate injury (leads to inflammation or degeneration)
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Inflammation
________: reaction of vascularized living tissue to local injury, irritants or agents.
3
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Irreversible
________: severe injury (leads to necrosis)
4
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Vascular dilation
________ leading to an increase in blood flow.
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Hotness is due to
increased blood flow
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redness is due to
vasodilatation and increased blood flow
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swelling is due to
exudate
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pain is due to
irritation of nerve endings by metabolites
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loss of function is due to
pain and tissue damage
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Cardinal Signs of Acute Inflammation
Hotness
Redness
Swelling
Pain
Loss of function
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General Signs of Acute Inflammation
1. Fever
2. Leukocytosis
3. C-reactive protein positive
4. Cloudy swelling of parenchymatous organs
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Two Major Components of Acute Inflammation
1. Vascular changes
2. Cellular events
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Benefits of Inflammation
1. Contain and isolate injury
2. Destroy invading microorganisms and inactive toxins
3. Prepare tissue for healing and repair
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Causes of Inflammation
Physical agents
Tissue necrosis
Foreign bodies
Chemical agents
Infection (most common cause)
Immunological
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most common cause of inflammation
Infection
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Types of Inflammatory Response
* Acute inflammation
* Chronic inflammation
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Tissue injury types
Reversible
Irreversible
18
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mild or moderate injury leads to
inflammation or degeneration
19
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severe injury leads to
necrosis
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severe injury
_______ leads to necrosis and is irreversible
21
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mild or moderate injury
_____ leads to inflammation or degeneration and is reversible